by Susann-C. Ruprecht, Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Brain slices of the mouse are placed onto a glass slide, for further imaging. Credit: David AusserhoferThere is growing evidence that peptide hormones from the gut have far-reaching effects on the whole organism. By binding to corresponding receptors in the brain, they can modulate food intake and...
by Tracey Peake, North Carolina State University Credit: Unsplash/CC0 Public DomainResearchers from North Carolina State University have pinpointed a particular peptide’s role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition. Atopic dermatitis (AD) is a skin condition characterized by itching, irritated and thickened skin at the site...
YUVAN RESEARCH INC. IMAGE: HIGH-RESOLUTION DERMAL ULTRASOUND SCAN OF ONE OF THE CLINICAL TRIAL VOLUNTEERS COMPARING THE INITIAL SKIN TO 3 MONTHS OF THE GHK-CU GEL USE. THE BRIGHTER THE IMAGE, THE HIGHER THE COLLAGEN DENSITY. CREDIT: © 2023 YUVAN RESEARCH INC. Skin loses collagen and elastin and becomes progressively thinner with age leading to wrinkles, so...
Could a naturally occurring peptide help tackle obesity-related diseases, including diabetes? Image credit: Spencer Platt/Getty Images. Peptides are smaller versions of proteins that have a range of purposes, such as the potential to reduce the signs of aging, relieve inflammation, or promote muscle growth. In 2015, researchers discovered a type of peptide called PEPITEM, and recognized its function...
GIFU UNIVERSITY IMAGE: THE MECHANISM OF GIPFA-085-MEDIATED INHIBITION OF DIET-INDUCED OBESITY IN MICE SHOWS THAT GIPS HAVE THERAPEUTIC POTENTIAL IN TREATING OBESITY AND DIABETES CREDIT: TOSHIHIKO YADA FROM GIFU UNIVERSITY The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese...
by University of Birmingham Credit: CC0 Public Domain Research published today in Clinical and Experimental Immunology shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver). The researchers used an animal model of obesity to investigate whether...
By Ben Coxworth January 26, 2023 Peptides in the spray kill bacteria (pictured) by damaging their protective outer membranes Depositphotos It’s always good if the use of antibiotics can be avoided, to keep harmful bacteria from developing a resistance to them. A new wound-treatment spray could help, as it kills bacteria using peptides that occur...
by University of California, Irvine Credit: iScience (2022). DOI: 10.1016/j.isci.2022.105901 A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS. The study, which appears in iScience, describes the first specific treatment designed to prevent the deadly disease, which can appear in patients with...
by Olga Kuchment, Texas A&M University Credit: Pixabay/CC0 Public Domain Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the brain, with therapeutic and scientific implications....
by Ludwig Cancer Research Credit: CC0 Public Domain The cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR) gene that are associated with the disease. The tail end of this gene’s mutated protein product (CALRMUT) should be an ideal neoantigen. Yet T cells directed against the CALRMUT fragment...
