Edited by Deepa Varma July 22, 2024 TOPLINE:Increased dietary intake of vitamin B1 is associated with a lower prevalence of constipation, particularly among men and individuals without hypertension or diabetes. METHODOLOGY:Researchers conducted a cross-sectional study using National Health and Nutrition Examination Survey data from 2005-2010 involving 10,371 adults aged ≥ 20 years.Participants provided information on...
Category: <span>Pharmaceutical Updates</span>
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Dual action antibiotic could make bacterial resistance nearly impossible
NEWS RELEASE 23-JUL-2024 Peer-Reviewed PublicationUNIVERSITY OF ILLINOIS CHICAGO A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research from the University of Illinois Chicago. For a new paper in Nature Chemical Biology, researchers probed how a class...
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New ‘vaccine-like’ HIV drug could cost just $40: Researchers
JULY 23, 2024 HIV infecting a human cell. Credit: NIHA new “vaccine-like” HIV drug that currently costs over $40,000 per person a year could be made for as little as $40, researchers estimated on Tuesday. The antiretroviral drug Lenacapavir, developed by US pharmaceutical giant Gilead, has been hailed as a potential game-changer in the fight...
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A new drug target identified for diseases associated with leukemia-causing virus
JULY 22, 2024 by Christine Yu, Pennsylvania State University KDR inhibition induces autophagic/lysosomal degradation of Tax. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49737-5A team of researchers from Penn State College of Medicine found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). They determined that blocking a class of enzymes...
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Cure for male pattern baldness given boost by sugar discovery
JULY 22, 2024 by University of Sheffield Microscopic analysis of skin sections retrieved on day 21 of experiment after H&E staining. Credit: Frontiers in Pharmacology (2024). DOI: 10.3389/fphar.2024.1370833The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according...
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Combination treatment based on drug repurposing shows promise in the treatment of retinal degenerations
NEWS RELEASE 22-JUL-2024 Peer-Reviewed PublicationUNIVERSITY OF EASTERN FINLAND Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications. A combination treatment incorporating three existing drugs – tamsulosin, metoprolol and bromocriptine – slowed disease progression in pre-clinical retinopathy models. Drug repurposing...
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NAD Benefits: From Healthy Aging to Higher Energy Levels
SCIENCE & TECHNOLOGY NEWS Ever wished there was a magic potion that could boost your energy, help you age gracefully, and boost your cognitive function? While it’s true that the fountain of youth is still undiscovered, NAD comes pretty close. This powerhouse molecule plays a vital role in many bodily functions. Research suggests NAD might...
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Metformin and other antidiabetic drugs can help reduce the risk of dementia in patients with type 2 diabetes
NEWS RELEASE 11-JUL-2024 Analysis of more than 1.5 million records of patients with type 2 diabetes casts light on the risk of dementia and Alzheimer’s disease and potential benefits associated with antidiabetic treatment, reports the American Journal of Preventive Medicine Peer-Reviewed PublicationELSEVIER IMAGE: RESULTS SHOW THAT THE FIRST-LINE ANTIDIABETIC DRUG METFORMIN AND THE SECOND-LINE SODIUM...
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60 years in the making: Nanoparticles revolutionize nucleotide delivery
By Tarun Sai LomteReviewed by Susha Cheriyedath, M.Sc.Jul 10 2024 A recent perspective article published in the journal Nature Reviews Drug Discoverydiscussed the evolution of lipid nanoparticles (LNPs) for nucleic acid delivery. The authors, Pieter Cullis, Professor of Biochemistry and Molecular Biology at the University of British Columbia, and Philip Felgner, Professor of Physiology and...
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An outdated vaccine could be to blame for LA’s COVID surge
An outdated vaccine could be to blame for LA’s COVID surgeRelaxed public measures, a new variant, and increased travel are also likely contributors to LA’s rising COVID cases.By Amber X. Chen • Published July 8, 2024 • Updated 2 hours agoCOVID-19 cases are on the rise in LA County and California. Colleen Williams and Annabelle...