Megan Brooks August 27, 2024 TOPLINE:Aspirin provides greater protection against colorectal cancer (CRC) in people with unhealthy lifestyles, particularly smokers with higher body weight, new data suggest. METHODOLOGY:Aspirin is an established agent for CRC prevention. Whether individuals with more lifestyle risk factors might derive greater benefit from aspirin remains unclear.Researchers analyzed regular aspirin use (defined...
Category: <span>Pharmaceutical Updates</span>
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Analysis finds no increased risk of mental health issues among those using semaglutide for weight loss
September 3, 2024 by Perelman School of Medicine at the University of Pennsylvania Credit: Unsplash/CC0 Public DomainTaking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders, according to a new study led by researchers from the Perelman School...
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Proof-of-principle study uncovers promising treatment for incurable prostate cancer
September 2, 2024 by Flinders University CDK9 is commonly over-expressed and amplified in prostate cancer. Credit: British Journal of Cancer (2024). DOI: 10.1038/s41416-024-02810-8Researchers from Flinders University and University of South Australia have unveiled a promising new strategy that could be used to treat the most aggressive forms of prostate cancer. Their study, published in British...
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Kidney disease medication found to reduce risk of cardiovascular death in certain heart failure patients in new study
By Jacqueline Howard, CNNPublished 6:00 AM EDT, Sun September 1, 2024 Few treatments are available for a type of heart failure that includes mildly reduced or preserved ejection fraction. simonkr/E+/Getty Images/File A medication that is currently used for chronic kidney disease in patients with type 2 diabetes has been found to reduce the risk of...
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Novel low-dose 3-in-1 blood pressure pill significantly outperforms standard care, study shows
August 31, 2024 by George Institute for Global Health Credit: Pixabay/CC0 Public DomainNew research shows that a treatment plan based on a novel combination of low doses of three anti-hypertensive drugs in a single pill—known as GMRx2—was superior to a high-quality standard care treatment plan at lowering blood pressure in patients with uncontrolled hypertension. Results...
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Vutrisiran offers a new lifeline to patients with progressive heart condition
August 30, 2024 by European Society of Cardiology Credit: Unsplash/CC0 Public DomainVutrisiran significantly improved mortality, cardiovascular events and markers of disease progression in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), according to late-breaking research presented in a Hot Line session held today, August 30, at ESC Congress 2024. “ATTR is a progressive, fatal disease in...
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Duloxetine may help elderly with depression and cognitive impairment
August 29, 2024 by Karolinska Institutet Credit: Pixabay.Karolinska Institutet has discovered that an already registered antidepressant, duloxetine, may also have positive effects on memory and cognitive functions in the elderly. A new study published in the journal ACS Omega shows that duloxetine, in addition to treating depression, also inhibits an enzyme involved in the regulation...
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miR-10b Inhibition: A strategy for treating metastatic breast cancer
News Release 28-Aug-2024 “We have developed a nanodrug, termed MN-anti-miR10b, that delivers anti-miR-10b antisense oligomers to cancer cells.” Peer-Reviewed PublicationImpact Journals LLC image: Figure 5: miR-10b inhibition by MN-anti-miR10b decreases Aldefluor accumulation and impairs spheroid formation. (A) Fluorescence microscopy of representative MDA-MB-231 cells after incubation with Aldefluor reagent. (B) Fluorescence microscopy of representative MCF-7 cells...
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First-generation antihistamines increase risk for seizures in children
September 4, 2024 by Lori Solomon First-generation antihistamines are associated with a higher seizure risk in young children, according to a study published online Aug. 28 in JAMA Network Open. Ju Hee Kim, M.D., from the Kyung Hee University Medical Center in Seoul, South Korea, and colleagues evaluated associations between prescriptions of first-generation antihistamines and...
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No HIV Infections After Twice-a-Year PrEP
Medscape Medical News Brian Owens July 05, 2024 Lenacapavir, a twice-yearly injectable HIV-1 capsid inhibitor, has shown 100% efficacy in preventing HIV in women at a high risk for infection, according to an interim analysis of the phase 3 PURPOSE 1 trial. The results were so promising that the independent data monitoring committee recommended that...