JULY 2, 2024 by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Credit: Andrea Piacquadio from PexelsExercise testing can serve as a powerful physiologic probe to unmask subclinical cardiovascular abnormalities well before disease onset. For example, blood pressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension. At present, there is...
Category: <span>Prognostic</span>
Electroconvulsive therapy or ketamine? Clinical factors affect outcomes
by UT Southwestern Medical Center Treatment outcomes of ketamine vs electroconvulsive therapy (ect) stratified by less or more severe baseline depression severity. The least-squares mean from mixed-effects model analyses was plotted for both treatment groups (ECT and ketamine) based on the 16-item Quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR16) baseline depression severity thresholds of moderate...
Circulating microRNAs likely as effective as A1C for predicting type 2 diabetes in youth, according to study
JUNE 24, 2024 by University of Oklahoma Nanostring miRNA analysis. From the initial screening including 11 participants with no treatment failure and 6 with treatment failure by the end of the clinical trial, 11 miRNA species were different at baseline and 16 were different at the end of study visit (approximately 8 years later) (P...
Brain connectivity on MRI predicts Parkinson’s disease progression
JUNE 25, 2024 by Radiological Society of North America Credit: Pixabay/CC0 Public DomainThe structural and functional organization of the brain as shown on MRI can predict the progression of brain atrophy in patients with early-stage, mild Parkinson’s disease, according to a study published today in Radiology, a journal of the Radiological Society of North America...
Psoriasis Linked to Higher Incidence of MACE Despite Statin Use
Over a period of 5 years, the likelihood of major adverse cardiovascular events (MACE) in patients with psoriasis and dyslipidemia who were on statin therapy was 40% greater than that in non-psoriasis patients with dyslipidemia on statin therapy, even after adjusting for covariates, results from a large retrospective study showed. “It is well-established that psoriasis...
Climate change is linked to worsening brain diseases
by Sanjay Sisodiya and Mark Maslin, The Conversation Credit: Pixabay/CC0 Public DomainClimate change is making the symptoms of certain brain conditions worse, our new review published in The Lancet Neurology has found. Conditions that can worsen as temperature and humidity rise include stroke, migraines, meningitis, epilepsy, multiple sclerosis, schizophrenia, Alzheimer’s disease and Parkinson’s. Our brains...
Alzheimer’s Starts Earlier and Progresses Faster in People With Down Syndrome
A new study revealed that Alzheimer’s disease starts earlier and progresses faster in people with Down syndrome.Original story from Washington University School of Medicine in St Louis A scientist in a white lab coat helps a person with Down syndrome into a brain scan machine.Washington University senior clinical research coordinator Brittany Nelson (front) helps study...
Simple blood test could predict risk of long-term COVID-19 lung problems
UNIVERSITY OF VIRGINIA HEALTH SYSTEM “THIS OFFERS HOPE THAT EVEN PATIENTS WITH THE WORST COVID DO NOT HAVE PROGRESSIVE SCARRING OF THE LUNG THAT LEADS TO DEATH,”SAID RESEARCHER Catherine A. Bonham, MD, A PULMONARY AND CRITICAL CARE EXPERT WHO SERVES AS SCIENTIFIC DIRECTOR OF UVA HEALTH’S INTERSTITIAL LUNG DISEASE PROGRAM. view moreCREDIT: UVA HEALTH UVA...
Research team uses AI to predict risk of liver cancer
by UC Davis Credit: Pixabay/CC0 Public DomainA team of UC Davis Health clinicians and data scientists has developed a machine-learning model to better predict which patients are at greater risk of developing a common type of liver cancer, hepatocellular carcinoma (HCC). The findings of their research—published in the journal Gastro Hep Advances—describe how predictive-learning can aid...
Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people
by University of Exeter Credit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start effective treatments. Optic neuritis is a condition that affects people of all ages, but especially young adults, usually manifesting in blurred vision and sometimes...