A common indicator of neurobiological disturbance among the elderly may also be associated with mortality, according to a study published August 9, 2017 in the open access journal PLOS ONE by Nicole A. Kochan at the Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney. Intraindividual reaction time variability (IIVRT), defined as an individual’s variation in reaction times...
Category: <span>Prognostic</span>
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Researchers Identify Strong Prognostic Indicators of Survival Following Pancreatic Tumor Removal
New Rochelle, NY, August 10, 2017—A new study of patients who underwent curative surgical removal of a pancreatic ductal adenocarcinoma showed that two of the nine preoperative factors analyzed were strongly predictive of poor prognosis regardless of the tumor stage. Preoperative assessment of these prognostic biomarkers might help in planning treatment strategies to improve patient outcomes,...
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Differences in subtypes of gastric cancer may determine prognosis and response to treatment
In 2014, The Cancer Genome Atlas (TCGA) project discovered that there are four molecular subtypes of gastric cancer: Epstein-Barr virus subtype (EBV); microsatellite instability subtype (MSI); genomically stable subtype (GS); and chromosomal instability subtype (CIN). Lee said most patients with early-stage gastric cancer are treated with a surgical resection, followed by chemotherapy. “However, outcomes vary...
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‘Fitness and fatness’: Not all obese people have the same prognosis; second study sheds light on ‘obesity paradox’
People can be obese but metabolically healthy and fit, with no greater risk of developing or dying from cardiovascular disease or cancer than normal weight people, according to the largest study ever to have investigated this seeming paradox. The findings show there is a subset of obese people who are metabolically healthy — they don’t...
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FDG-PET appears promising for predicting prognosis of patients with inoperable NSCLC
The prognosis for patients with stage II and III inoperable non-small cell lung cancer (NSCLC) is poor, with only about 15 percent of patients surviving at five years post-treatment for the disease. While new treatment strategies are being intensely studied, timely assessment of their efficacy has proven difficult. In a presentation today, Mitchell Machtay, MD,...
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Discovery of biomarkers for the prognosis of chronic kidney disease
Currently, there is no effective method to predict the prognosis of chronic kidney disease (CKD) patients. Tomonori Kimura and Yoshitaka Isaka, researchers in Department of Nephrology, Osaka University, found that measuring D-amino acids※1, which present only trace in human, provides prognostic information of CKD. The present discovery would facilitate CKD treatment and thus improve the...