by Bob Yirka, Medical Xpress Linear relation between NPI score (grand-mean-centered) and facial muscle activity in the negative and neutral feedback condition. Panel a depicts an interaction between feedback and grandiose narcissism on the log-transformed and baseline-corrected orbicularis oculi (OO) muscle activity. Panel b presents the same interaction effect on the log-transformed and baseline-corrected corrugator...
by Dr. André Schmidt and Professor Claudio De Simone, Medical Xpress Uncinate fasciculus (UF) tract DTI tractography. (A) Virtual dissection of UF. Green lines at the coronal slice represents the ‘AND’ gates for the virtual dissection. Virtually dissected left and right UF shown in sagittal view. (B) Fractional anisotropy (FA) of UF. The factorial ANOVA...
by University of Illinois at Chicago Credit: University of Illinois at Chicago With scarce clinical resources unable to keep pace with elevated rates of mental illness, technological solutions could help decrease waitlists and disparities in access to therapy. Recent advances in artificial intelligence have fueled interest in the use of chatbots and virtual assistants for mental...
by University of Montreal PNN components and metalloproteases are expressed by different cell types in mouse PFC. a Single cell RNA-sequencing (DropSeq) of PFC cells of P40-43 wild-type mice (n = 8 mice). t-SNE visualization of identified cell types; cluster 9 refers to PV+ cells. b–d Expression localization of critical components of PNN structure and remodeling, including lecticans (b...
By Michael Irving May 17, 2023 Stanford scientists have uncovered a new mechanism behind depression – and shown how magnetic stimulation can help treat it. Depositphotos Stanford scientists have discovered a major biological mechanism behind severe depression, and shown how to treat it. Signals between two key parts of the brain seem to flow the...
by Leah Eisenstadt, Broad Institute of MIT and Harvard Protein changes at brain cell synapses from patients with schizophrenia were strikingly similar to those from patients with bipolar disorder. Credit: Sonja Vasiljeva/Broad Institute Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some...
by Elsevier Comparison between controls and deletion carriers, GABA+ and Glx levels in: a) Anterior cingulate cortex (ACC), b) Hippocampus and c) Superior Temporal Cortex (STC). Compared to controls, deletion carriers were found to have higher levels of Glx in the hippocampus and STC and lower levels of GABA+ in the hippocampus. The lines in the...
Scientists have developed a potential anti-depressant that exhibits anti-stressing as well as anti-depressant effects with minimal side effects Peer-Reviewed Publication TOKYO UNIVERSITY OF SCIENCE IMAGE: RESEARCHERS FROM JAPAN DEMONSTRATE THAT A DOP AGONIST, KNT-127, ALTERS THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS, HIPPOCAMPAL NEUROGENESIS, AND NEUROINFLAMMATION, TO EXHIBIT THERAPEUTIC AND PROPHYLACTIC EFFECTS CREDIT: “202102 FRONTAL PLANE OF THE BRAIN HIPPOCAMPUS”...
by European Society of Cardiology Credit: Pixabay/CC0 Public Domain Adults in their 20s and 30s with mental disorders have an up to three-fold elevated likelihood of a heart attack or stroke, according to a study in more than 6.5 million individuals published today in the European Journal of Preventive Cardiology,. Lifestyle behaviors did not explain the excess...
by NYU Langone Health Credit: Pixabay/CC0 Public Domain Led by researchers from NYU Grossman School of Medicine and University of Szeged in Hungary, a new study in mice and rats found that restoring certain signals in a brain region that processes smells countered depression. Publishing in the journal Neuron online May 9, the study results revolve around nerve...
