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Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (C) Illustration of the timeline of events within a single day of imaging. (D) Schematic of the experimental setup used to image bioluminescence in the mouse. Credit: NeuroImage (2024). DOI: 10.1016/j.neuroimage.2024.120882 University of Rochester researchers have...

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Brain activity can predict success of depression treatment

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial,” currently available online and scheduled to appear...