Most neurons last a lifetime, but new neurons are still produced by neural stem cells. Stanford researchers identified genes, like GLUT4, that could help reactivate neural stem cells in aging brains, offering hope for neuron regeneration. New research hints at ways to generate neurons. Most neurons in the human brain last a lifetime, and for...
Category: <span>Stem Cell Therapy</span>
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Canada and Australia curb predatory stem cell market: Researchers hope to replicate success in US
Over the last decade, a number of U.S. clinics have marketed stem cell products directly to consumers as purported treatments for a host of diseases and injuries. The problem is that many of these interventions have scant proof of efficacy or safety, noted Laertis Ikonomou, Ph.D., associate professor of oral biology in the University at...
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Exciting advance in stem cell therapy
SCIENCE & TECHNOLOGY NEWS A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential. Surgery – illustrative photo. Image credit: Max Pixel, CC0 Public Domain Stem cell therapy has been heralded as a new way to treat many...
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Researchers pioneer novel stem cell therapy for diabetic wound healing
by TranSpread Hypoxia facilitates exosome production and release from BMSCs. (a) Transmission electron microscopy (TEM) revealed the morphology of noBMSC-Exos and hyBMSC-Exos (scale bar: 100 nm). (b) The size distribution of noBMSC-Exos and hyBMSC-Exos was examined using nanoparticle tracking analysis (NTA). (c and d) Western blotting analysis for exosome surface marker proteins, including CD9, CD63,...
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Genetically Modified Pluripotent Stem Cells May Evade Immunological Rejection After Transplantation
Researchers say the genetically engineered stem cells also could pave the way for new regenerative medicine treatments for diseases such as Type 1 diabetes. Deepta Bhattacharya, who is on the University of Arizona Health Sciences Center for Advanced Molecular and Immunological Therapies advisory council, is a professor of immunobiology in the UArizona College of Medicine...
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New study on promising stem cell-based therapy for Crohn’s disease
by Liam Connolly, UC Davis Schematic showing putative mechanism of hMSCs mediated immunosuppression in experimental model of Crohn’s disease. Credit: npj Regenerative Medicine (2024). DOI: 10.1038/s41536-024-00347-1A stem cell therapy for Crohn’s disease developed by UC Davis Health researchers has shown promising results in mouse studies. The research, published in npj Regenerative Medicine, showed that human bone...
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Newly discovered stem cell offers clues to a cancer mystery
By Mark Johnson Scientists have discovered a new type of stem cell in the spine that appears crucial to resolving a long-standing mystery: why far more cancer cells spread to the spine than to other bones in the body. When breast, lung and prostate cancers metastasize to multiple bones in the body, three to five...
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Stem Cell Research Paves Way Toward Regenerating Skeletal Muscle
UCLA researchers have made headway using muscle stem cells to regrow damaged muscle in mice. Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA are one step closer to developing stem cell therapies to regenerate skeletal muscle in humans. Working in mice, the UCLA team discovered how...
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Does stem cell transplantation benefit patients with knee osteoarthritis?
by Wiley Credit: CC0 Public DomainCell therapy represents a potential regenerative treatment for osteoarthritis. A recent analysis of all relevant published studies indicates that stem cell transplantation from different sources is effective for treating knee osteoarthritis, the most prevalent chronic joint disease. The review and meta-analysis, which is published in the Journal of Orthopaedic Research,...
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Study shows stem cell transplant significantly improves outcomes in refractory juvenile systemic sclerosis
by American College of Rheumatology Credit: CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all measures for two years following autologous stem cell transplant.Juvenile-onset systemic sclerosis (jSSc), also called scleroderma, is a disfiguring autoimmune disorder...