Peer-Reviewed PublicationHONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY IMAGE: A MODEL OF HOW STEM CELL NICHE USES THE PROTEIN CHANNELS “GAP JUNCTIONS” TO TRANSPORT ITS CAMP INTO STEM CELL PROGENY IN CONTROLLING THEIR DIFFERENTIATION INTO FUNCTIONAL CELLS. CREDIT: HKUST Researchers at the Hong Kong University of Science and Technology (HKUST) have found how stem cells’...
by City University of Hong Kong The transplanted SOX9-suppressed neural stem cells (bottom) at injured site generated robust axons extending into the host spinal cord after 3 months post-graft. Credit: Advanced Science (2023). DOI: 10.1002/advs.202205804 A research team co-led by City University of Hong Kong (CityU) and The University of Hong Kong (HKU) has recently made a significant...
UNIVERSITY OF MINNESOTA MEDICAL SCHOOL MINNEAPOLIS/ST. PAUL (07/06/2023) — Published in the Journal of Clinical Oncology, University of Minnesota Medical School researchers led a study that demonstrated the safety of using microbiota transplant therapy (MTT) in patients with acute myeloid leukemia (AML) — a type of blood cancer — and recipients of hematopoietic cell transplantation (HCT). Current...
by Nara Institute of Science and Technology The gastric corpus, which is a major component of the glandular stomach, is composed of parietal, chief, pit, and neck cells. Each of these specialized epithelial cells play an important role in digestion, and they are continuously replenished by new ones which are formed via the differentiation of...
Scientists may have made a breakthrough in the treatment of baldness by using a tiny RNA particle to stimulate hair growth. The study revealed that hair follicles become stiff with age, making it harder for hair to grow. However, by softening the stem cells through the production of a specific RNA called miR-205, researchers at Northwestern University...
by Zen Logsdon, City of Hope National Medical Center City of Hope’s Yanhong Shi, Ph.D., and her colleagues engineered healthy human skin cells containing the functional aspartoacylase (ASPA) gene into induced pluripotent stem cells (iPSCs) and then differentiated the iPSCs into oligodendroglial progenitor cells, the precursor cells that produce myelin, an insulating sheath that wraps around...
by Justin Jackson , Phys.org Allogeneic HIP islets achieve long-term survival. a, Immunofluorescence pictures of dissociated and reaggregated wtallo and HIPallo islets from rhesus monkeys (representative images). b, In vitro insulin secretion of wtallo and HIPallo islets (mean ± s.d., triplicates). c, The composition of wtallo and HIPallo islets of α, β, δ and other cells (mean, triplicates). d, Flow cytometry...
LUND UNIVERSITY Researchers at Lund University Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major...
by Justin Jackson , Medical Xpress Graphical abstract. Credit: Cell (2023). DOI: 10.1016/j.cell.2023.02.017 Researchers at Stanford University in California have devised a fluorescence-activated cell-sorting method for isolating distinct neural stem and progenitor cell types from human brain tissue. The markers used in the study are conserved across diverse brain regions. The technique should aid future research on...
INSTITUT PASTEUR The team in the Hematology Department at Henri Mondor AP-HP Hospital, coordinated by Dr. Christine Robin, and scientists from the Institut Pasteur (the Invasive Bacterial Infections Unit led by Professor Muhamed-Kheir Taha) recently studied protection against meningococcal infection in patients who had received hematopoietic stem cell transplantation. The results of this trial (NCT03509051), sponsored by...
