U.S. Phase 2 Study to Begin in First Quarter of 2019 NEW YORK, Dec. 17, 2018 — BrainStorm Cell Therapeutics Inc. (NASDAQ: BCLI), a leading developer of innovative autologous adult stem cell therapeutics for debilitating neurodegenerative diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted the Investigational New Drug (IND) application...
Category: <span>Stem Cell Therapy</span>
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Maintaining the unlimited potential of stem cells
Salk scientists discover new protein complex that keeps embryonic stem cells at stage of fullest potential, a key to regenerative medicine SALK INSTITUTE LA JOLLA–(December 11, 2018) Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start...
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New insight into stem cell behaviour highlights therapeutic target for cancer treatment
Research led by the University of Plymouth and Technische Universität Dresden has identified a new therapeutic target for cancer treatment and tissue regeneration – a protein called Prominin-1. Dr Bing Hu. Credit: University of Plymouth Dr. Bing Hu from Plymouth’s Institute of Translational and Stratified Medicine (ITSMed), together with Dr. Denis Corbeil from the Technische...
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Stem cell researchers develop promising technique to generate new muscle cells in lab
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON To help patients with muscle disorders, scientists at The University of Texas Health Science Center at Houston (UTHealth) have engineered a new stem cell line to study the conversion of stem cells into muscle. Findings appeared in Cell Reports. IMAGE: UTHEALTH STEM CELL RESEARCHERS, FROM THE LEFT, ARE NADINE MATTHIAS, DVM; JIANBO WU, PH.D.; RADBOD DARABI, M.D., PH.D.; AND...
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Are Stem Cells the Future of Effective Back Pain Treatment?
According to the National Institute of Neurological Disorders and Stroke, 80 percent of Americans will have at least one episode of lower (or lumbar) back pain in their lifetimes. Discomfort or pain in the cervical and thoracic regions is common as well, with an estimated third or so of Americans living with pain at any...
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Queen bee’s secret sauce uncovers a key ingredient that keeps stem cells young
The simply named and intriguingly effective royal jelly is what separates queen bees from the rest. These lucky bees are selected by the colony during the larval stage and coated in the milky, nutritious substance and then go on to become large and fertile leaders of the pack. For the first time, scientists at Stanford...
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Proposed cancer treatment may boost lung cancer stem cells, study warns
Study adds evidence that cancer stem cells drive adenocarcinoma; suggests new strategy that makes tumor cells less “stem-like” BOSTON CHILDREN’S HOSPITAL Epigenetic therapies — targeting enzymes that alter what genes are turned on or off in a cell — are of growing interest in the cancer field as a way of making a cancer less...
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Treating the ‘bubble babies’
An international study published in the journal Blood by researchers led by Dr. Elie Haddad, a pediatric immunologist and researcher at CHU Sainte-Justine and professor at Université de Montréal, highlights the urgent need to develop better treatment strategies for patients suffering from severe combined immune deficiency (SCID). This deficiency, better known as “bubble baby disease”...
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Gene PPM1D gives stem cells a ‘winning boost’ after chemotherapy
Chemotherapy has been associated with an increased risk of leukemia years after the treatment, but what leads to that association is not clear. In this study published in the journal Cell Stem Cell, a team led by researchers at Baylor College of Medicine and MD Anderson Cancer Center combined clinical and laboratory studies to show...
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Stem cells can differentiate into neurons and may be useful post-stroke therapeutics
Researchers have performed a careful comparison between locally generated, ischemia-induced, multipotent stem cells (iSCs) and bone marrow-derived mesenchymal stem cells (BM-MSCs) in an effort to determine which cell type has greater central nervous system (CNS) repair capacity. Their results show that the iSC characteristics make them more promising candidates as CNS injury therapeutics. The study...