After a heart attack, the heart can undergo several structural and functional changes. Even after oxygen delivery to the heart muscle has been restored, a temporary loss of contractile function can persist for several hours or even days. This phenomenon is called myocardial stunning and it can also occur in people who have undergone cardiovascular...
Category: <span>Stem Cell Therapy</span>
Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier
Researchers at the University of South Florida show in a new study that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier. In a study recently published in the journal Scientific Reports, researchers in USF’s...
Researchers identify ‘signal’ crucial to stem cell function in hair follicles
Jeff Biernaskie’s research identifies a factor essential for dermal stem cells to continuously divide during tissue regeneration. Stem cell researchers at the University of Calgary have found another piece of the puzzle behind what may contribute to hair loss and prevent wounds from healing normally. Jeff Biernaskie’s research, published recently in the scientific journal npj...
Success of stem cell therapy for diabetes depends on pre-transplant immune condition
An innovative method for treating type 1 diabetes based on the transplantation of hematopoietic stem cells taken from the patient’s own bone marrow began undergoing testing in Brazil 13 years ago. The results were highly variable. While some of the volunteers were able to stop self-injecting insulin for more than a decade, others had to...
Injured bones reconstructed by gene and stem cell therapies
This illustration shows the bone-tissue engineering technique developed by Cedars-Sinai investigators. ‘Endogenous MSCs’ refers to stem cells from a patient’s bone. The ‘BMP gene’ is a gene that promotes bone repair. A Cedars-Sinai-led team of investigators has successfully repaired severe limb fractures in laboratory animals with an innovative technique that cues bone to regrow...
Key stem cells for repairing knee joints identified
Key stem cells for repairing knee joints identified by Aberdeen scientists. Stem cells that seem key for maintaining and repairing the body’s knee joints have been identified by scientists. Researchers from the University of Aberdeen’s Centre for Arthritis and Musculoskeletal Health published the findings today (Tuesday May 16) in Nature Communications. Our joints are surrounded...
Stem cells may significantly improve tendon healing by regulating inflammation
New research published online in The FASEB Journal suggests that tendon stem (TSCs) may be able to significantly improve tendon healing by regulating inflammation, which contributes to scar-like tendon healing and chronic matrix degradation. This has implications for the treatment of acute tendon injuries and chronic tendon disease. “Inflammation plays a critical role in acute and chronic tendon...
Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier
ALS mice improved with stem cell therapy; first step for science in finding better treatment Researchers at the University of South Florida show in a new study that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the...
Let there be tissue: More precise, controlled method of engineering tissues from stem cells
Near-infrared light is used to precisely engineer stem cells into tissue. Nothing beats nature. The diverse and wonderful varieties of cells and tissues that comprise the human body are evidence of that. Each one of us starts out as a mass of identical, undifferentiated cells, and thanks to a combination of signals and forces, each...
Key stem cells for repairing knee joints identified
Key stem cells for repairing knee joints identified by Aberdeen scientists. Stem cells that seem key for maintaining and repairing the body’s knee joints have been identified by scientists. Researchers from the University of Aberdeen’s Centre for Arthritis and Musculoskeletal Health published the findings today (Tuesday May 16) in Nature Communications. Our joints are surrounded...