Former British number one died of primary sclerosing cholangitis in 2014 Doctors in Birmingham are offering new hope with a trial starting this year The cells are taken from umbilical-cord blood, taken from donations to NHS Stem cells harvested from umbilical-cord blood are to be used in a new treatment for the liver disease that...
Category: <span>Stem Cell Therapy</span>
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Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy
Abstract BACKGROUND: Bone marrow mesenchymal stem cells (BMMSCs) and bone marrow mononuclear cells (BMMNCs) are both used to treat spastic cerebral palsy. However, the differences in therapeutic effect remain unknown. METHODS: A total of 105 patients with spastic cerebral palsy were enrolled and randomly assigned to three groups: the BMMSC group, the BMMNC group and...
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Treatment of Cerebral Palsy with Stem Cells: A Report of 17 Cases
Abstract Cerebral Palsy (CP) is a disabling condition that affects a child’s life and his/her family irreversibly. It is usually a non-progressive condition but improvement over time is rarely seen. The condition can be due to prenatal hypoxia, metabolic, genetic, infectious, traumatic or other causes. It is therefore a heterogeneous group that results in functional...
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Magnet-Bead Based MicroRNA Delivery System to Modify CD133+ Stem Cells
Abstract Aim. CD133+ stem cells bear huge potential for regenerative medicine. However, low retention in the injured tissue and massive cell death reduce beneficial effects. In order to address these issues, we intended to develop a nonviral system for appropriate cell engineering. Materials and Methods. Modification of human CD133+ stem cells with magnetic polyplexes carrying microRNA was studied...
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Mesenchymal Stem Cell Administration in Patients with Chronic Obstructive Pulmonary Disease: State of the Science
Abstract Patients with chronic obstructive pulmonary disease (COPD) have chronic, irreversible airway inflammation; currently, there is no effective or curative treatment and the main goals of COPD management are to mitigate symptoms and improve patients’ quality of life. Stem cell based therapy offers a promising therapeutic approach that has shown potential in diverse degenerative lung...
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Spherical biodegradable carriers support scalable and cost-effective stem cell expansion and bone formation
Stem cells (red) on polycaprolactone-based microcarriers. Bone tissue engineering is theoretically now possible at a large scale. A*STAR researchers have developed small biodegradable and biocompatible supports that aid stem cell differentiation and multiplication as well as bone formation in living animal models. Mesenchymal stem cells self-renew and differentiate into fat, muscle, bone, and cartilage cells, which makes them...
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Stem Cells Applications in Regenerative Medicine and Disease Therapeutics
Abstract Regenerative medicine, the most recent and emerging branch of medical science, deals with functional restoration of tissues or organs for the patient suffering from severe injuries or chronic disease. The spectacular progress in the field of stem cell research has laid the foundation for cell based therapies of disease which cannot be cured by...
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Immune cell therapy on liver cancer using interferon beta produced with stem cells
(A) Bio-imaging analysis to evaluate the therapeutic effect of iPS-ML producing IFN-β on metastatic liver cancer. (B) Quantification of the image data shown in A. (C) Histological data indicating migration of iPS-ML (PKH26, red) into …more Causes of the most common form of liver cancer, hepatocellular carcinoma (HCC), include hepatitis B or C, cirrhosis, obesity,...
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Molecular roadmap of human stem cell states
Use of the immunofluorescent microscopy visualization technique reveals the presence of specific proteins in naive human embryonic stem cells. The stem cells have been colored to represent the different proteins detected in this study. Researchers have identified a set of molecular ‘flags’ that are present on the surface of human stem cells. Stem cells are...
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Just ONE injection of stem cells from a man’s stomach could be a permanent cure for impotence (and even help them to lose weight)
Trial results show the therapy effectively restores spontaneous sexual function Each man had a small sample of fat taken from their stomach using liposuction Findings could pave the way for treatment for men who don’t respond to Viagra The approach would be particularly valuable for men made impotent by surgery A single injection of stem...