Study: Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations. Image Credit: Silver Place/Shutterstock.com A recent study published in Brain performed ultrahigh field quantitative susceptibility mapping (QSM) of the brainstem in coronavirus disease 2019 (COVID-19) survivors post-hospitalization. Introduction Neuroradiological changes have been reported in hospitalized COVID-19 patients. Cerebral microhemorrhages, white matter hyperintensities, and encephalopathy are...
Category: <span>Treatment</span>
Adding vagus nerve stimulation to training sessions may boost how well sounds are perceived
Peer-Reviewed Publication NYU Langone Health / NYU Grossman School of Medicine Just as a musician can train to more sharply distinguish subtle differences in pitch, mammals can improve their ability to interpret hearing, vision, and other senses with practice. This process, which is called perceptual learning, may be enhanced by activating a major nerve that...
A novel approach to combat fatty liver disease
Peer-Reviewed Publication Ecole Polytechnique Fédérale de Lausanne Metabolic dysfunction-associated steatotic liver disease (MASLD) — previously known as “non-alcoholic fatty liver disease” — affects about 25% of the global population. Its severe form, metabolic dysfunction-associated steatohepatitis (MASH), can lead to liver fibrosis and even liver failure. With only one approved treatment currently available, finding solutions for...
IS A NEW SCHIZOPHRENIA DRUG REALLY A GAME CHANGER?
A new drug is being hailed as a breakthrough for the 2.8 million American adults (among 24 million people worldwide) who battle schizophrenia. The US Food & Drug Administration (FDA) has greenlit Bristol Myers Squibb’s Cobenfy, reportedly making it the first major new treatment for the disorder in 70 years. Unlike other antipsychotic drugs, Cobenfy appears to...
Epigenetic test could help predict efficacy of immunotherapy in multiple myeloma
Epigenetic characterization of PVR shows the correlation between promoter DNA methylation and expression. Credit: Leukemia (2024). DOI: 10.1038/s41375-024-02419-z Multiple myeloma is a type of blood cancer that appears mainly after the age of 60. Its incidence, therefore, increases with the aging of the population. In this pathology, the bone marrow, the porous structure within the bones that...
Scrutinizing cells for clues to a treatment for muscular dystrophy
Characteristics of Ad-MSCs, BM-MSCs, and XF-iMSCs. Credit: Stem Cell Research & Therapy (2024). DOI: 10.1186/s13287-024-03951-6 A research team led by Associate Professor Hidetoshi Sakurai and Researcher Nana Takenaka-Ninagawa recently demonstrated the superior therapeutic potential of iPS cell-derived mesenchymal stromal cells (iMSCs) compared to primary MSCs as a potential treatment for Ullrich congenital muscular dystrophy. The study is published in Stem...
Ablation Technology: Innovations and Industry Overview
What is ablation technology? Ablation therapy consists of a minimally invasive treatment, which can be used for treating cancer by destroying tumors and other abnormal tissues within the body. It uses either extremely high or low temperatures to remove a layer or layers of tissue. However, radiofrequency energy or electrical currents can also be used.1...
Gut hormones could hold the key to fighting fatty liver disease
The accumulation of fats in the liver is driven by high-fat diets and obesity, and is becoming an increasingly prevalent global health concern. Characterized by excessive fat accumulation in the liver, this condition poses significant risks for various metabolic disorders. While much of the existing research has focused on fat metabolism within the liver itself,...
Promising cell therapy offers hope for relapsed or refractory T-cell leukemia
Antileukemia activity of anti-CD7 PEBL-CAR T cells. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-03228-8 A new cell therapy, targeting CD7 in leukemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukemia (T-ALL) who have exhausted all standard treatment options. Published in the journal Nature Medicine on 3 September 2024, the study highlights the effectiveness of a new chimeric...
Botox: Six surprising uses that have nothing to do with smoothing wrinkles
Botulinum toxin, or Botox as it’s widely known, is famous for its ability to smooth away wrinkles. But hiding our frown lines from the world isn’t the reason early scientists started experimenting with this substance. Botulinum toxin is produced by the bacterium Clostridium botulinum. In its most raw form, it can cause the deadly disease...