Still, after the trial’s results were published, a question remained unanswered: “Why would weight loss lead to diabetes remission in some people?”
Now, researcher Roy Taylor — from Newcastle University in the United Kingdom — who oversaw DiRECT, together with colleagues from various academic institutions, claim that they may have found the answer.
Their observations were published in the journal Cell Metabolism.
Weight loss can normalize blood sugar
For DiRECT, the researchers recruited participants who had been diagnosed with type 2 diabetes within 6 years from the start of the trial.
For the study, the volunteers were randomly split into two groups: some were assigned best-practice care, acting as the control group, while others joined an intensive weight management program while still receiving appropriate care for diabetes.
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