Stem cells can develop into many different types of cells, such as muscle cells, red blood cells, or neurons....
Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas
Highlights Sumoylation regulates CD44 and MMP14 expression in basal breast and colon cancer SUMO inhibition clears cancer stem cells, repressing...
Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas
Highlights Sumoylation regulates CD44 and MMP14 expression in basal breast and colon cancer SUMO inhibition clears cancer stem cells, repressing...
Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural Progenitors
Highlights iENPs can be converted from fibroblasts using hESC-ENP enriched factors iENPs exhibit cellular and molecular characteristics resembling hESC-ENPs iENPs...
Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural Progenitors
Highlights iENPs can be converted from fibroblasts using hESC-ENP enriched factors iENPs exhibit cellular and molecular characteristics resembling hESC-ENPs iENPs...
Discovery of superparamagnetism in sub-millimeter-sized magnetite porous single crystals
Abstract In this work, sub-millimeter-sized magnetite porous single crystals were found to exhibit unique superparamagnetism rather than the known ferrimagnetism....
Combination of NSAIDs and TNF-inhibitors shows benefit for ankylosing spondylitis
WASHINGTON — A combination of nonsteroidal anti-inflammatory drugs and TNF-inhibitors may help slow down spine damage in ankylosing spondylitis, according...
Novel technologies and emerging bio-markers for personalized cancer Immunotherapy
Abstract The culmination of over a century’s work to understand the role of the immune system in tumor control has...
KEYTRUDA WORKS WITH YOUR IMMUNE SYSTEM TO HELP FIGHT CANCER CELLS
KEYTRUDA is not chemotherapy or radiation therapy—it is an immunotherapy and it works with your immune system to help fight...
Tricky gene mutations detected by new easy-to-use DECoN software
Photo: Jan Chlebik/the ICR Scientists have developed an easy-to-use software tool that can detect important genetic mutations that previously needed...