Highlights Sumoylation regulates CD44 and MMP14 expression in basal breast and colon cancer SUMO inhibition clears cancer stem cells, repressing...
December 17, 2016December 17, 2016
Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas
Highlights Sumoylation regulates CD44 and MMP14 expression in basal breast and colon cancer SUMO inhibition clears cancer stem cells, repressing...
December 17, 2016December 17, 2016
Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural Progenitors
Highlights iENPs can be converted from fibroblasts using hESC-ENP enriched factors iENPs exhibit cellular and molecular characteristics resembling hESC-ENPs iENPs...
December 17, 2016December 17, 2016
Direct Conversion of Human Fibroblasts into Neural Progenitors Using Transcription Factors Enriched in Human ESC-Derived Neural Progenitors
Highlights iENPs can be converted from fibroblasts using hESC-ENP enriched factors iENPs exhibit cellular and molecular characteristics resembling hESC-ENPs iENPs...
December 05, 2016December 5, 2016
Discovery of superparamagnetism in sub-millimeter-sized magnetite porous single crystals
Abstract In this work, sub-millimeter-sized magnetite porous single crystals were found to exhibit unique superparamagnetism rather than the known ferrimagnetism....
December 05, 2016December 5, 2016
Combination of NSAIDs and TNF-inhibitors shows benefit for ankylosing spondylitis
WASHINGTON — A combination of nonsteroidal anti-inflammatory drugs and TNF-inhibitors may help slow down spine damage in ankylosing spondylitis, according...
December 05, 2016December 5, 2016
Novel technologies and emerging bio-markers for personalized cancer Immunotherapy
Abstract The culmination of over a century’s work to understand the role of the immune system in tumor control has...
December 05, 2016December 5, 2016
KEYTRUDA WORKS WITH YOUR IMMUNE SYSTEM TO HELP FIGHT CANCER CELLS
KEYTRUDA is not chemotherapy or radiation therapy—it is an immunotherapy and it works with your immune system to help fight...
December 05, 2016December 5, 2016
Tricky gene mutations detected by new easy-to-use DECoN software
Photo: Jan Chlebik/the ICR Scientists have developed an easy-to-use software tool that can detect important genetic mutations that previously needed...
December 05, 2016December 5, 2016
Blood test determines type of cancer
The scalpel-free biopsy that can pinpoint cancer: New blood test helps oncologists tell the difference between types of the deadly...