Tag: <span>3D structure</span>

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Hepatitis: 3D structure determination of the ‘gateway’ to the liver
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Hepatitis: 3D structure determination of the ‘gateway’ to the liver

CNRS IMAGE: ILLUSTRATION OF THE TWO 3D CONFORMATIONS ADOPTED BY NTCPS. LEFT: ‘OPEN’ CONFORMATION TO WHICH HBV AND HDV CAN BIND. RIGHT: ‘CLOSED’ CONFORMATION THAT PREVENTS RECOGNITION BY THE VIRUSES. CREDIT: © KAPIL GOUTAM/NICOLAS REYES/CNRS Though an essential gateway to the liver, NTCP had not been well described until now. Na+-taurocholate co-transporting polypeptide (NTCP) is...

Regulation of the genome affects its 3D structure
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Regulation of the genome affects its 3D structure

INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: DNA METHYLATION HAS AN INTRINSIC EFFECT ON 3D GENOME STRUCTURE. CREDIT: IRB BARCELONA All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell “reads” different chapters of the genome, thus producing alternative sets of...