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Early diagnosis and treatment of Alzheimer’s disease by targeting toxic soluble Aβ oligomers
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Early diagnosis and treatment of Alzheimer’s disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University (A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all side chains have been omitted. (C) Structures of cyclic D,L-α-peptide 1 and azaGly-cyclopeptides (2-7). Credit: Proceedings of the National Academy of Sciences (2022). DOI: 10.1073/pnas.2210766119 More than 55 million people worldwide were...