Credit: Unsplash/CC0 Public Domain For some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and causing cancer. But despite causing major disease, these slightly mutated proteins can resemble their normal versions so closely that treatments designed to target mutants could also harm...
Tag: <span>A HER2</span>
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A HER2-targeting peptide drug conjugate with better penetrability for effective breast cancer therapy
by Compuscript Ltd Schematic diagram and pharmacokinetics of HER2-TP-cy5.5 and HER-TA-cy5.5 conjugate synthesis. (A) Schematic representation of the utilization of HER2-targeting peptide/antibody and Cyanine5.5-NHS ester (Cy5.5) to form conjugates. (B) Purification of the conjugates, (C) Collection of the purified components. (D) The circulation time of free Cy5.5 and Cy5.5-labeled peptide/antibody after intravenous injection in mice...