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New monoclonal antibodies targeting ACE2 receptor could treat the next waves of SARS-CoV-2

by Justin Jackson , Medical Xpress Inhibition of authentic SARS-CoV-2 infection by human anti-hACE2 mAbs. a,b, Anti-hACE2 mAbs (2G7A1, 05H02, 05B04 and the hybrid antibody 05B04LC/05D06HC) were serially diluted and incubated with Vero E6 and Huh-7.5 target cells (a) or Vero E6 target cells only (b). Thereafter, cells were infected with authentic SARS-CoV-2 (WA1/2020) (a...