by Yale School of Medicine In a new study, researchers including Yale School of Medicine’s Michael Simons, MD, identify the molecular underpinnings of persistent endothelial-to-mesenchymal transition (EndMT), an important process related to vascular inflammation in diseases including pulmonary hypertension. Researchers found atypical acetate production from glucose triggered metabolic modulation of the endothelium activated TGF-β signaling, triggering a...