by American Society of Nephrology Credit: Pixabay/CC0 Public Domain Glucagon-like peptide-1-receptor agonists (GLP-1RA) are medications that are increasingly prescribed for patients with type 2 diabetes and congestive heart failure. Reports of GLP-1RA–associated acute kidney injury (AKI) have emerged, but the risk of GLP-1RA–associated AKI among patients on anti-cancer drugs is unclear. Surprisingly, new research suggests that...
Tag: <span>acute kidney injury</span>
Post
Older adults with acute kidney injury face higher dementia risk
August 26, 2024 by Karolinska Institutet Credit: Unsplash/CC0 Public DomainAcute kidney injury is associated with an increased risk of developing dementia, according to a new study published in the journal Neurology by researchers at Karolinska Institutet and others. Acute kidney injury (AKI), a sudden deterioration in kidney function, is relatively common in older people and...
Post
Blood mutations increase risk for acute kidney injury, says study
by Vanderbilt University Medical Center Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized adults...
Post
Migraine drug shows promise in treatment of acute kidney injury
by American Physiological Society Graphical abstract. Credit: American Journal of Physiology-Renal Physiology (2022). DOI: 10.1152/ajprenal.00249.2022 The drug lasmiditan, which is used to treat migraines, shows promise as a possible treatment for acute kidney injury, according to a new study from the University of Arizona. The findings are published ahead of print in the American Journal of Physiology–Renal Physiology....
Post
Chinese Medical Journal review explores the role of macrophages in the progression of acute kidney injury to chronic kidney disease
CACTUS COMMUNICATIONS IMAGE: ROLE OF MACROPHAGES IN THE TRANSITION TO CHRONIC KIDNEY DISEASE, AND THE THERAPEUTIC STRATEGIES TO BLOCK THIS TRANSITION, ARE EXPLORED. CREDIT: CHINESE MEDICAL JOURNAL Acute kidney injury (AKI) is a condition in which kidneys are unable to filter waste from the blood effectively, leading to various health complications. Numerous studies have demonstrated...
Post
Metals found in people’s urine could detect acute kidney injury in very early stages, says new study
by Charlotte Anscombe, University of Nottingham Credit: Pixabay/CC0 Public Domain Scientists have discovered that certain metals found in people’s urine, could be potentially useful clinical biomarkers for the early detection of acute kidney injury (AKI). The study, which is published in Kidney International Reports, was led by experts from the University of Nottingham’s School of Veterinary...
Post
Similar rates of COVID-related acute kidney injury found in early adolescents and older adults
by Hannah Echols, University of Alabama at Birmingham Credit: University of Alabama at Birmingham Acute kidney injury (AKI) is increasingly recognized as a significant complication caused by COVID-19 infection. Researchers from the University of Alabama at Birmingham and Children’s of Alabama studied the epidemiology of coronavirus-related AKI and discovered peaks in AKI in early adolescents...
Post
Plasma biomarkers predict long-term kidney function after acute kidney injury
IMAGE: PLASMA BIOMARKERS MEASURED THREE MONTHS AFTER HOSPITALIZATION DEMONSTRATE UTILITY IN ASSESSING AKI PATIENTS FOR LONG-TERM CKD RISK. CREDIT: PLEASE CITE AS “VISUAL ABSTRACT FOR WILSON M ET AL, BIOMARKERS DURING RECOVERY FROM AKI AND PREDICTION OF LONG-TERM REDUCTIONS IN ESTIMATED GFR, AMERICAN JOURNAL OF KIDNEY DISEASES (2021), DOI: HTTPS:// DOI.ORG/10.1053/J.AJKD.2021.08.017.” A panel of plasma biomarkers...
Post
Strong immune response underlies acute kidney injury related to COVID-19
MAYO CLINIC ROCHESTER, Minn. — Mayo Clinic researchers have found that acute kidney injury associated with COVID-19 resembles sepsis-caused kidney injury, and the immune response triggered by the infection plays a pivotal role. The findings, published in Mayo Clinic Proceedings, also suggest that mitochondrial dysfunction — a loss of function in cellular energy production — is commonly found in...
Post
Prolonged exposure to extreme heat and humidity increases risk of acute kidney injury
EXPERIMENTAL BIOLOGY IMAGE: HAYDEN HESS, PHD CREDIT: HAYDEN HESS Rockville, Md. (April 27, 2021)–Exposure to extreme heat (95 degrees Fahrenheit and above) and humidity for eight hours raises the core body temperature and causes dehydration, resulting in an increased risk of acute kidney injury, according to a new study. The researchers, from the Indiana University School...
- 1
- 2