CIC BIOGUNE IMAGE: APAP-INDUCED DILI LEADS TO DYSREGULATION OF AMMONIA LEVELS. THE NEGATIVE MODULATION OF MIR-873-5P RESTORES METHIONINE CYCLE ACTIVITY, ATTENUATES AMMONIA ACCUMULATION, AND INCREASES POLYAMINE SYNTHESIS ACTIVITY. ALL IN ALL, THESE FACTS IMPROVE THE REGENERATIVE CAPACITY AND THUS RESTORE THE PHYSIOLOGICAL ACTIVITY OF THE LIVER. CREDIT: RUBEN RODIGUEZ, CIC BIOGUNE Acute liver failure is...
