by Children’s Hospital of Philadelphia Arrest states of T-ALL subtypes in reference to human hematopoiesis. Credit: Nature Cancer (2024). DOI: 10.1038/s43018-024-00863-5 Researchers from Children’s Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients with acute lymphoblastic leukemia who have a higher risk version of the disease and are more likely to relapse...
Tag: <span>Acute lymphoblastic leukaemia</span>
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‘Capicua’ gene plays a key role in T-cell acute lymphoblastic leukaemia
T-ALL mouse model with inactivated CIC/CAPICUA (staining with CD3 antibodies highlighting aberrant T cells). Researchers at the Spanish National Cancer Research Centre (CNIO) have discovered a genetic alteration that is directly involved in at least 10 percent of cases of a common cancer in children, T-cell acute lymphoblastic leukaemia. In a paper published this...