Illustration of T cell activation by APC (using CD4 T cells as an example). The TCR recognizes and binds to the pMHC complex presented by the APC. The coreceptor CD4 binds to the MHC class II molecule, generating the first signal, which induces T cell activation. Additionally, the binding of CD80 and CD86 on the...
Tag: <span>adaptive immunity</span>
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Booster immunization in same limb as the first shot yielded stronger adaptive immunity in mice
by Bob Yirka, Medical Xpress Credit: Unsplash/CC0 Public Domain A collaboration between researchers at Duke University and Harvard Medical School has shown that mice receiving a booster shot in the same limb resulted in stronger adaptive immunity than a shot in another limb. In their paper published in the journal Science Immunology, the group describes their...
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Adaptive human immunity depends on the factor responsible for the formation of white blood cells
Granulocyte colony-stimulating factor (G-CSF) has a significant regulatory effect not only on innate, but also on adaptive immunity. IMMANUEL KANT BALTIC FEDERAL UNIVERSITY Granulocyte colony-stimulating factor (G-CSF), which causes division and differentiation of bone marrow cells depending on the body’s need for leukocytes, has a significant regulatory effect not only on innate, but also on...