With increased life expectancy, age-associated cognitive decline becomes a growing concern, even in the absence of recognizable neurodegenerative disease. The integrated stress response (ISR) is activated during aging and contributes to age-related brain phenotypes. We demonstrate that treatment with the drug-like small-molecule ISR inhibitor ISRIB reverses ISR activation in the brain, as indicated by decreased...
by IOS Press By following a group of newly diagnosed patients with Parkinson’s disease (PD) for a decade or more, researchers have been able to identify several factors never before reported that appear to be associated with higher mortality rates in PD patients compared to the general population. As reported in the Journal of Parkinson’s...
New study looks at timing and number of mentally stimulating activities AMERICAN ACADEMY OF NEUROLOGY MINNEAPOLIS – A new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social activities are linked to a lower risk or delay of age-related memoryloss called mild cognitive impairment, and that...
New study looks at timing and number of mentally stimulating activities MINNEAPOLIS – A new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social activities are linked to a lower risk or delay of age-related memory loss called mild cognitive impairment, and that the timing and...
