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Ceramides accumulate in the aged muscle – Researchers identify a new hallmark of ageing

UNIVERSITY OF HELSINKI Researchers have uncovered sphingolipid accumulation as a new mechanism that affects ageing. Ceramides, the best-known class of sphingolipids, accumulate in aged muscle, impairing its function while also affecting functional capacity in older adults. These findings encourage researchers to develop potential pharmaceutical agents. A study carried out at the University of Helsinki and...