by King’s College London Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-56299-7 New research published in Nature Communications reveals how cancer cells are altered by their surroundings, enabling them to change their shape and break out of a tumor. The discovery, which is the culmination of almost a decade of research that began at King’s, paves the way for treatments that will tackle cancer...
Tag: <span>aggressive cancer</span>
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Triple combination of inhibitors emerges as potential new treatment for aggressive cancer
by Germans Trias i Pujol Research Institute In vivo testing of the three selected combinations in the NF1-associated MPNST PDOX mouse model. A, Relative tumor volume growth of the NF1-18B PDOX mouse model during the 2 weeks of treatment in each group. B, Waterfall plot of the fold change of each individual tumor at the...
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New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial
by Queen Mary, University of London Credit: Pixabay/CC0 Public DomainAn innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by Queen Mary University of London. The findings have been published in JAMA Oncology....
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DNA discovery may assist in fight against aggressive cancer
by University of Otago Graphical abstract. Credit: iScience (2023). DOI: 10.1016/j.isci.2023.106986 In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer. Led by Associate Professor Aniruddha Chatterjee and Drs Euan Rodger and Rachel Purcell, researchers discovered abnormalities in the DNA instruction code that lead...
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Cancer drug: New treatment halts tumour growth
By Rachel Schraer Health reporter A drug that could stop cancer cells repairing themselves has shown early signs of working. More than half of the 40 patients given berzosertib had the growth of their tumours halted. Berzosertib was even more effective when given alongside chemotherapy, the trial run by the Institute of Cancer Research (ICR)...
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Some types of prostate cancer may not be as aggressive as originally thought
by University of California, Los Angeles Researchers at the UCLA Jonsson Comprehensive Cancer Center analyzed gene-expression patterns in the most aggressive prostate cancer grade group—known as Gleason grade group 5—and found that this grade of cancer can actually be subdivided into four subtypes with distinct differences. The findings may affect how people are treated for...
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People with type 2 diabetes and heart disease may benefit from newer therapies
by American Heart Association Type 2 diabetes (T2D) affects treatment options for patients who have both coronary artery disease (CAD) and T2D, according to a new American Heart Association Scientific Statement, published today in the Association’s flagship journal Circulation. The scientific statement provides an overview of the latest advances for treating people who have both...