ATT may be more sensitive to age-related decline than CBF, and therefore useful for early detection and management of cerebrovascular impairment.”Peer-Reviewed Publication Impact Journals LLC Figure 4. Flow chart of the screening and experimental sessions. Abbreviations: MoCA: Montreal Cognitive Assessment; ECG: electrocardiogram; MRI: magnetic resonance imaging; CBF: cerebral blood flow; ATT: arterial transit time; GMV: grey matter...
Tag: <span>Aging</span>
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Out with the old, in with the new: the science behind memory clutter and aging
News Release 17-Sep-2024 Boston University researchers uncover how memory maintenance and deletion shape cognitive decline in aging Peer-Reviewed PublicationBoston University Ever feel like those catchy song lyrics or random pieces of trivia won’t leave your head, and it’s affecting your memory? Boston University associate professor of psychological & brain sciences Dr. Rob Reinhart, along with...
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Not just a normal part of aging: Dizziness in older adults is linked to higher risk of future falls
September 18, 2024 by Imperial College London Credit: Pixabay/CC0 Public DomainThe first meta-analysis of its kind has shown a conclusive link between older adults experiencing spells of dizziness and a dramatically elevated risk of falling. The study, “Association between dizziness and future falls and fall-related injuries in older adults: a systematic review and meta-analysis,” is...
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Small RNA molecule plays role in driving aging, research confirms
September 11, 2024 by Kendall Daniels, University of North Carolina at Chapel Hill School of Medicine The liver of miR-29TG and 2 year-old wildtype mice share changes in key aging-related genes and pathways. Credit: Communications Biology (2024). DOI: 10.1038/s42003-024-06735-zA team led by UNC School of Medicine researchers is the first to confirm that a small...
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The Molecular Secret to Longevity: Scientists Have Discovered a “Lifespan Limit Line”
By Eötvös Loránd University September 8, 2024 Scientists have identified a “mitochondrial epigenetic clock” involving 6mA in mtDNA, which may revolutionize aging research by providing new insights into lifespan regulation and potential interventions for healthier aging.Building on their groundbreaking research in epigenetics and transposable elements related to aging, scientists at Eötvös Loránd University have achieved...
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Fish gut facials fight wrinkles and age spots
Health & Wellbeing By Paul McClureSeptember 06, 2024 Bacteria in the guts of some species of seabream have anti-aging propertiesDALL-E You might soon be buying anti-aging skincare products containing fish guts, thanks to a new study that found that the innards of two species of seabream possess compounds that fight wrinkles and age spots. There...
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Gene regulation study finds coordination between basic cellular processes is lost with increasing age
September 3, 2024 by Gabriele Meseg-Rutzen, University of Cologne Representative gene–gene relationship changes with age, captured by pairwise correlation and a GRN-based approach. Credit: Nature Aging (2024). DOI: 10.1038/s43587-024-00696-yGene regulation in our cells—the decision on which proteins are produced for the various processes of the cell—is strictly regulated. It has long been assumed that this...
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Proteomic and secretomic analysis reveals cytoskeleton’s role in aging
September 3, 2024 by Impact Journals LLC FLNB and ACTC1 analysis. (A) mRNA FLNB expression (RT-qPCR) of fibroblasts in quiescence or after 24h of TGF-β-1 stimulation (Mean±SEM, n= 6 for young and old cells); (B) mRNA expression quantified by RT-qPCR after transfection with specific siRNA for FLNB (siFLNB) or with Scramble siRNA (siScramble), in quiescence...
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Study explores the cell-type-specific effects of aging and sex on human cortical neurons
September 3, 2024 by Ingrid Fadelli , Medical Xpress (A) Study design. (B) UMAP embedding of nuclei assigned to 11 excitatory, 10 inhibitory, and 3 glial types using DNA methylation in 100 kb bins. (C) RNA expression and gene body DNA methylation at non-CG sites (mCH) for cell type marker genes. (D) Correspondence of mRNA,...
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Longevity Breakthrough: New Treatment Reverses Multiple Hallmarks of Aging
By University of Texas M. D. Anderson Cancer Center September 2, 2024 Researchers have shown that restoring youthful levels of a telomerase subunit can significantly alleviate aging signs in models, potentially impacting age-related diseases like Alzheimer’s and cancer. Their study identified a compound that maintains the telomerase reverse transcriptase (TERT) levels, reducing cellular aging, inflammation,...