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Chronic Inflammation Negatively Impacts Proteostasis in Aging Tissues
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Chronic Inflammation Negatively Impacts Proteostasis in Aging Tissues

Proteostasis describes the steady-state of a cell, maintaining an appropriate balance of various forms of protein machinery in order to enable continued normal function. With advancing age, proteostasis becomes disrupted in numerous complicated ways. This is a downstream outcome of underlying molecular damage, the reactions to that damage, and the immediate consequences of that damage....