by Rutgers University Credit: CC0 Public DomainAdults 65 and older who were hospitalized for a variety of medical conditions had highly satisfying conversations about whether they wanted CPR, regardless of whether doctors used the terms “allow a natural death” or “do not resuscitate” for indicating no CPR, according to a pilot study by Rutgers Health...
by Johns Hopkins University School of Medicine Ashani Weeraratna, Ph.D. Credit: Will Kirk/JHUAge-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center. The study, published March 12 in...
Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions. Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and from older adults. These...
Peer-Reviewed Publication MAYO CLINIC With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, often referred to as zombie cells. However, zombie cells linger and contribute to various age-related health problems and diseases....
By Dr. Priyom Bose, Ph.D.Feb 13 2024Reviewed by Benedette Cuffari, M.Sc. Aging is associated with many biological, physiological, and psychological changes, some of which include a decline in cognitive function, greying of hair, frailty, and increased risk of contracting certain diseases. Aging also increases the risk of chronic diseases such as diabetes, hypertension, and cardiovascular...
Cold Spring Harbor LaboratoryThe fountain of youth has eluded explorers for ages. It turns out the magic anti-aging elixir might have been inside us all along. Cold Spring Harbor Laboratory (CSHL) Assistant Professor Corina Amor Vegas and colleagues have discovered that T cells can be reprogrammed to fight aging, so to speak. Given the right...
Peer-Reviewed PublicationUNIVERSITY OF CALIFORNIA – SAN FRANCISCO Could a Drug Prevent Hearing Loss from Loud Music and Aging?Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss. A person’s hearing can be damaged by loud noise, aging and even certain...
Autophagy genes help extrude protein aggregates from neurons in the nematode C. elegans Peer-Reviewed Publication BUCK INSTITUTE FOR RESEARCH ON AGING Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and...
A healthy smile helps us live long, well and happy lives. But just like our bodies, our teeth succumb to age-related changes. So what happens to teeth as you age? And what can you do to ensure your smile lasts the distance?First, what are teeth made of? The tooth crown is covered by a hard...
Researchers from Osaka University have shown for the first time that damaged lysosomes are repaired by a process called microautophagy, which is essential for preventing aging Peer-Reviewed Publication OSAKA UNIVERSITY OVERVIEW: LYSOSOMES ARE REPAIRED BY ESCRT-DRIVEN MICROAUTOPHAGY, AND STK38 AND GABARAPS ARE KEY REGULATORS OF THIS PROCESS BY RECRUITING ESCRTS TO LYSOSOMES. THESE REGULATORS ARE...
