Tag: <span>Aging</span>

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“phase separation” allows an RNA to tightly control the activity of a protein that regulates neurodegeneration and aging
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“phase separation” allows an RNA to tightly control the activity of a protein that regulates neurodegeneration and aging

UT SOUTHWESTERN MEDICAL CENTER IMAGE: IMAGE SHOWS CELLS WITH OIL DROPLET-LIKE ‘NORAD-PUMILIO BODIES’ IN RED AND NUCLEUS IN BLUE. CREDIT: MAHMOUD ELGUINDY CREDIT: MAHMOUD ELGUINDY DALLAS – June 9, 2021 – A phenomenon in which an RNA named NORAD drives a protein named Pumilio to form liquid droplets in cells, much like oil in water,...

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Scientists map gene changes underlying brain and cognitive decline in aging

ELIFE  Alzheimer’s disease shares some key similarities with healthy aging, according to a new mathematical model described today in eLife.  The model provides unique insights into the multiscale biological alterations in the elderly and neurodegenerative brain, with important implications for identifying future treatment targets for Alzheimer’s disease.  Researchers developed their mathematical model using a range of biological...

On the Aging Adaptive Immune System
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On the Aging Adaptive Immune System

An interesting fact about the adaptive immune system: the number of T cells in the body remains much the same across the entire lifespan, even after the supply of new T cells all but ceases in middle age. T cells are created as thymocytes by hematopoietic cells in the bone marrow, and then mature in...

Declining Resilience as a Manifestation of Aging
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Declining Resilience as a Manifestation of Aging

Resilience, meaning the ability to recover from wounds, infection, and other forms of damage, is more or less the flip side of frailty in aging. Frailty increases, resilience decreases. A damaged system is less robustly resilient to further damage, as reliability theory tells us. Degenerative aging is precisely an accumulation of cell and tissue damage at the molecular level,...

Cytoplasmic traffic jam disrupts sleep-wake cycles
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Cytoplasmic traffic jam disrupts sleep-wake cycles

by  The Korea Advanced Institute of Science and Technology (KAIST) Figure 1. PER abundance oscillates in a circadian manner through an autoregulatory negative feedback loop. This oscillation enables robust timekeeping of circadian-timed physiological and behavioral processes including sleep. Credit: The Korea Advanced Institute of Science and Technology (KAIST) KAIST mathematicians and their collaborators at Florida State...

Glutamine protects against muscle injuries and aging
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Glutamine protects against muscle injuries and aging

by  VIB (the Flanders Institute for Biotechnology) Representative images of embryonic myosin heavy chain (eMyHC) expression in TA muscle 6 days after CTX injury. A team headed by Prof. Massimiliano Mazzone (VIB-KU Leuven Center for Cancer Biology), in collaboration with Dr. Emanuele Berardi and Dr. Min Shang, revealed a new metabolic dialogue between inflammatory cells and...

Yoga May Bolster the Brain Regions Most Affected by Aging
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Yoga May Bolster the Brain Regions Most Affected by Aging

By Claudia Wallis | Scientific American November 2020 Issue I’ll be honest: I’m something of a yoga nut. I’ve practiced for decades and recently became a certified yoga teacher. But, to be honest again, some of the health claims I’ve heard about yoga make me squirm. Does yoga really fix poor digestion? How on earth can it regulate...

Senolytics: A New Weapon in the War on Aging
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Senolytics: A New Weapon in the War on Aging

Anti-aging drugs that remove harmful cells from our bodies could treat a range of diseases that plague the elderly. By Nathaniel Scharping Getting old means fighting a war you’ll never win. Our bodies already battle for us every day, against bacteria and viruses, mutant cells, harmful chemicals and the slow rush of time itself. But...

The key to minimizing health risks associated with aging
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The key to minimizing health risks associated with aging

by The Westmead Institute for Medical Research  Credit: CC0 Public Domain Researchers hope developing therapies that target CD47 will significantly reduce the impact these health issues have on older individuals and health systems globally. During old age, some of the body’s most important functions, like the formation of new blood vessels, blood flow and metabolism...

Medical myths: All about aging
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Medical myths: All about aging

In the latest installment of our Medical Myths series, we tackle myths associated with aging. Because aging is inevitable and, for some people, frightening, it is no surprise that myths abound. Addressing the “inevitabilities” of aging. To discover more evidence-based information and resources for healthy aging, visit our dedicated hub. Around 300,000 generations ago, the human species...