OREGON HEALTH & SCIENCE UNIVERSITY A form of gene therapy currently used to treat Parkinson’s disease may dramatically reduce alcohol use among chronic heavy drinkers, researchers at Oregon Health & Science University and institutions across the country have found. The study in nonhuman primates showed that implanting a specific type of molecule that induces cell growth effectively...
Tag: <span>Alcohol use disorder</span>
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People with alcohol use disorder impaired after heavy drinking, despite claims of higher tolerance
by University of Chicago Credit: Pixabay/CC0 Public Domain While heavy drinkers can tolerate a certain amount of alcohol better than light or moderate drinkers, the concept of “holding your liquor” is more nuanced than commonly believed, according to new research from the University of Chicago. The researchers conducted the study with three groups of young adults...
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Study finds hepatitis C treatment gap for individuals with alcohol use disorder
by NIH/National Institute on Alcohol Abuse and Alcoholism Credit: Unsplash/CC0 Public Domain A new study supported by the National Institutes of Health shows that individuals with alcohol use disorder (AUD) are less likely to receive antivirals for hepatitis C, despite current guidelines recommending antiviral treatment regardless of alcohol use. Direct-acting antiviral treatment is highly effective...
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Targeting dysregulated kappa-opioid receptors reduces working memory deficits in alcohol use disorder
UNIVERSITY OF SOUTH FLORIDA (USF HEALTH) IMAGE: STUDY PRINCIPAL INVESTIGATOR BRENDAN WALKER, PHD, A NEUROSCIENTIST AT THE UNIVERSITY OF SOUTH FLORIDA HEALTH (USF HEALTH) MORSANI COLLEGE OF MEDICINE, STUDIES BIOLOGICAL BRAIN CHANGES THAT DRIVE ADDICTIVE BEHAVIORS. CREDIT: USF HEALTH/UNIVERSITY OF SOUTH FLORIDA TAMPA, Fla (March 9, 2022) — As heavy or frequent alcohol use escalates, some...
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Multi-omics approach identifies large list of candidate genes associated with alcohol use disorder
by The Mount Sinai Hospital Credit: Pixabay/CC0 Public Domain Researchers from the Icahn School of Medicine at Mount Sinai have published the first study of its kind in the field of addiction genetics using a multi-omics approach to provide a large list of causal candidate genes associated with alcohol consumption and alcohol use disorder (AUD). The study...
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Dual-drug therapy shows promise for treating alcohol use disorder
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO UCSF researchers have leveraged two new molecules, one of which is currently in clinical oncology trials, to devise a dual-drug therapy for alcohol use disorder (AUD), without the side effects or complications associated with current treatment regimens. The approach had highly successful results in mice and may be applicable to other...
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Ketamine could help men suffering from alcohol use disorder
Research from Florida State University is giving physicians a better understanding of ketamine, a potentially useful tool in treating depression that still has unanswered questions. A team of researchers working in the laboratory of Mohamed Kabbaj, a professor of Biomedical Sciences and Neuroscience in the College of Medicine, showed that ketamine can decrease alcohol consumption in male rats that...