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The key to depression, obesity, alcoholism – and more? Why the vagus nerve is so exciting to scientists
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The key to depression, obesity, alcoholism – and more? Why the vagus nerve is so exciting to scientists

Linda Geddes I’ve made a cup of coffee, written my to-do list and now I’m wiring up my ear to a device that will send an electrical message to my brainstem. If the testimonials are to believed, incorporating this stimulating habit into my daily routine could help to reduce stress and anxiety, curb inflammation and...

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A drug that cures alcoholism may be the next anti-anxiety medication

TOKYO UNIVERSITY OF SCIENCE Alcoholism, if left untreated, could have dangerous repercussions. Thus, it is no surprise that there are a range of drugs developed to treat this condition. Of these drugs, disulfiram (DSF) is approved by the Food and Drug Agency (FDA) for the treatment of alcoholism. DSF primarily inhibits the enzyme aldehyde dehydrogenase...

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Ketamine an ‘Intriguing New Therapy’ for Alcoholism

Megan Brooks January 25, 2022 Three weekly infusions of the dissociative anesthetic ketamine coupled with mindfulness-based relapse prevention therapy may help adults with alcohol use disorder (AUD) maintain abstinence, new research suggests. Preliminary results from a phase 2, double-blind, placebo-controlled trial show ketamine was well tolerated and, compared with placebo, associated with more days of...

Novel pharmacological strategies to treat alcoholism. Focus on epigenetics
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Novel pharmacological strategies to treat alcoholism. Focus on epigenetics

BENTHAM SCIENCE PUBLISHERS IMAGE: ALCOHOL INFLUENCES EPIGENETIC MODIFICATIONS AFFECTING DIFFERENT BIOMOLECULES’ FUNCTIONING–DRUG DESIGN SEARCHES FOR COMPOUNDS THAT MODULATE EPIGENETIC MECHANISMS. REPRESENTATIONS OF BIOMOLECULES ARE FROM PROTEIN DATA BANK; CODE FOR HISTONES IS 3AFA, DNA representation is from doi.org/105281/zenodo.4012404. CREDIT: DR. F. DAVID RODRIGUEZ Abusive alcohol drinking considerably impacts human health. Alcoholism, better defined as Alcohol...

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Does Drinking Alcohol Cause Joint Pain in Arthritis?

By Dr. Sanchari Sinha Dutta, Ph.D. Reviewed by Dr. Jennifer Logan, MD, MPH Image Credit: DimaBerlin / Shutterstock Arthritis is a disease of joints, characterized most commonly by joint swelling, stiffness, and pain. Although several studies suggest that drinking alcohol is associated with a lower chance of developing rheumatoid arthritis, there are also numerous studies showing that...

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Marijuana may boost risky effects of drinking alcohol

by Pennsylvania State University As the legalization of medical marijuana and marijuana use are both on the rise in the United States, people are not necessarily using alcohol less and may be unaware of the risks of combining alcohol and marijuana, according to researchers. A new study from Penn State found that compared to people...

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Why does my face go red after drinking alcohol?

By Nicole Galan Reviewed by J. Keith Fisher, M.D. Some people develop a distinctive facial flush after drinking alcohol, when their face turns either slightly or very red. Why does this happen, and what does it mean? This side effect of drinking alcohol is more common in people of East Asian descent. Although it does not cause immediate health problems, it...

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Moderate alcohol consumption does not protect against stroke, study shows

by  Lancet Blood pressure and stroke risk increase steadily with increasing alcohol intake, and previous claims that 1-2 alcoholic drinks a day might protect against stroke are dismissed by new evidence from a genetic study involving 160,000 adults. Studies of East Asian genes that strongly affect how much alcohol people choose to drink show that alcohol itself directly increases blood pressure and the chances of having...

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Study finds women seek and resist help for alcoholism in different ways than men

A new study from the University of Iowa finds that women are less likely to get help for a drinking problem and are more likely to believe the problem will get better on its own. The study, which digs deep into the differences in the way men and women handle excessive alcohol consumption, suggests that different strategies for dealing with the problem should be developed for men and women. “We should ask ourselves, ‘How...

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New target could prevent progression of liver damage to cancer

AUGUSTA, Ga. (Aug. 27, 2018) – Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report. The relentless, increased activity of TREM-1 in turn accelerates injury and scarring of the liver, a first step toward cirrhosis and liver cancer,...

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