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Allegra vs. Benadryl: 8 Differences Between These 2 Allergy Medications

supersizer/iStock via Getty Images Plus Allegra (fexofenadine) and Benadryl (diphenhydramine) are two antihistamines available over the counter (OTC). They can both help relieve allergy symptoms in adults and children. But they have some notable differences. For instance, Benadryl is a first-generation (older) antihistamine, while Allegra is a third-generation (newer) antihistamine. This distinction means that Allegra tends to have fewer side effects, among...

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Antihistamine Side Effects: When to Stop Taking Allergy Medication

By Dr. Liji Thomas, MD | Reviewed by Dr. Jennifer Logan, MD, MPH Skip to: Antihistamines Sedating antihistamines Central side effects Anticholinergic and alpha-adrenergic side effects Cardiac side effects Side effects with geriatric use Contraindications to sedating antihistamines Non-sedating antihistamines Conclusion Allergies have gone up by 40% in recent years, and allergy medications are being used more often than ever before. There are various types...