Tag: <span>allopurinol</span>

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Adverse Events Compared for Colchicine, NSAID Gout Flare Prophylaxis When Starting Allopurinol

Heidi Splete October 06, 2023TOPLINE:Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. METHODOLOGY:The researchers conducted two matched retrospective cohort studies using the UK Clinical Practice Research Datalink and the Hospital Episode Statistics primary...

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Allopurinol dose escalation for gout doesn’t improve mortality

(HealthDay)—Allopurinol dose escalation is not associated with reductions in mortality risk among patients with gout, according to a study published in the August issue of Arthritis & Rheumatology. Brian W. Coburn, Ph.D., from the University of Nebraska Medical Center in Omaha, and colleagues assessed whether allopurinol dose escalation is associated with cause-specific mortality in patients with...