Tag: <span>ALS disease</span>

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Pharmacological inhibitor protects nerve cells in ALS disease

Heidelberg neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patientsPeer-Reviewed Publication HEIDELBERG UNIVERSITY A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral...

Predicting development of ALS disease with AI methods
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Predicting development of ALS disease with AI methods

by Bielefeld University The architecture of DiseaseCapsule. The input is the concatenation of the compressed features from all Gene-PCA models, where each feature corresponds to one Gene-PCA. The number of Gene-PCAs is 75,584, so the dimensionality of the input is 75,584 × 1. DiseaseCapsule consists of three layers: a fully connected layer (FC), a primary capsule layer...