by Karolinska Institutet Progression rate of newly diagnosed ALS patients. ALS patients were stratified by the proportion of T cell subsets in the blood (A) and cerebrospinal fluid (B) at the time of diagnosis. The longitudinal evolution of ALS functional rating scale-revised (ALSFRS-R) in relation to the baseline categories of T cell subsets is plotted...
by The Spanish National Cancer Research Centre Mouse motor neurons, generated from mouse embryonic stem cells exposed (right) or not (left) to ALS-associated peptides (right). As observed in patients, these peptides are toxic and cause neuronal death. Credit: CNIO In amyotrophic lateral sclerosis (ALS), the progressive death of neurons that control body movement leads to paralysis of muscles...
The 68-year-old woman hadn’t been able to talk for a decade. She’d been on a ventilator and a feeding tube since 2007 and hadn’t been able to so much as blink an eye to communicate since 2010. For all anyone knew, she was a human shell, made completely immobile by amyotrophic lateral sclerosis, also known...
