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New treatment reverses Alzheimer’s disease signs, improves memory function in preclinical study
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New treatment reverses Alzheimer’s disease signs, improves memory function in preclinical study

by Perelman School of Medicine at the University of Pennsylvania PBA treatment reduces PERK activity and increases XBP1s in the hippocampus of APPNL-G-F knock-in (KI) mice. Confocal images of the hippocampus across groups. (A) BiP in the CA3. (B) p-PERK in the CA3. (C) ATF4 in the CA1. (D) XBP1s in the CA3. (E) ADAM10 in...