by American Heart Association Credit: Pixabay/CC0 Public Domain The same risk factors that contribute to making heart disease the leading cause of death worldwide also impact the rising global prevalence of brain disease, including stroke, Alzheimer’s disease and dementia, according to the American Heart Association’s Heart Disease and Stroke Statistics—2022 Update, published today in the...
by Alzheimer’s Research UK Experiment protocol. (a) EEG electrode positions for surgical implantation. E1 and E2 indicate electrodes on the frontal and parietal cortex, respectively, while reference electrode (R) was placed on cerebellum. G and A correspond to the electrodes for animal grounding and the anchoring screw, respectively. Red dots denote the location of implants...
GIST (GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY) IMAGE: ULTRASOUND STIMULATION AS AN EFFECTIVE THERAPY FOR ALZHEIMER’S DISEASE CREDIT: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY With the increase in average life expectancy in many parts of the world, certain age-related diseases have become more common. Alzheimer’s disease (AD), unfortunately, is one of them, being extremely prevalent...
by University of Seville Fig. 1. Generation of NrxnCTF transgenic mice. A) Schematic drawings showing the proteolytic processing of Nrxns by metalloproteases and PS (left) and the HA-tagged NrxnCTF transgene used in this study (right). The regions recognized by the HA and the cyto-Nrxn antibodies are indicated. LNS, Laminin/Neurexin/Sex hormone binding-globulin domain; TM, transmembrane region....
SOCIETY FOR NEUROSCIENCE IMAGE: THE BRAINS OF THE COGNITVELY FRAIL MORE CLOSELY RESEMBLE THE BRAINS OF HEALTHY CONTROLS THAN THOSE OF ADULTS WITH ALZEHEIMER’S DISEASE OR A MILD COGNITIVE IMPAIRMENT. CREDIT: KOCAGONCU ET AL., JNEUROSCI 2022 At the first sign of cognitive trouble, people often worry Alzheimer’s disease is forthcoming. But poor cognition can be...
by Thomas Olafsen and Elin Doeland, University of Oslo The green colors show healthy mitochondria while the red ones are damaged mitochondria undergoing “clearance” by mitophagy. Credit: Xu-xu Zhuang One in six Norwegians over 80 is affected by Alzheimer’s disease. Numbers are even higher worldwide, and there is still no cure available. Researchers at the...
by Case Western Reserve University PET scan of a human brain with Alzheimer’s disease. Credit: public domain An international team led by Case Western Reserve University’s School of Medicine has made a significant breakthrough in understanding why Alzheimer’s disease progresses so rapidly in some people that they die within three years. The researchers found a...
by Molly Chiu, Baylor College of Medicine Credit: Baylor College of Medicine The brain has a natural protective mechanism against Alzheimer’s disease, and researchers at Baylor College of Medicine, Texas Children’s Hospital, and collaborating institutions have discovered that gene variants associated with risk of developing the disease disturb the protective mechanism in ways that can...
by University of Helsinki Credit: Pixabay/CC0 Public Domain A study conducted at the University of Helsinki and the Helsinki University Hospital (HUS) suggests that the APOE4 allele may also increase cerebral microhaemorrhages related to COVID-19 and associate with mental fatigue related to long COVID. Roughly one-third of Finns carry the APOE4 allele, a genetic variant that...
by University of Adelaide Credit: Pixabay/Pete Linforth. A team of researchers at the University of Adelaide has found a link between the way that cells produce energy for brain function and the mutated genes found in Alzheimer’s disease. The discovery published in Disease Models and Mechanisms has prompted further examination of the link as a fundamental, early...
