by University of Gothenburg Credit: Unsplash/CC0 Public Domain In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer’s disease can detect the disease early and track its course, which has major implications for a potential use in clinical practice and treatment trials. “This is...
A major mystery in Alzheimer’s disease research is why some brain cells succumb to the creeping pathology of the disease years before symptoms first appear, while others seem impervious to the degeneration surrounding them until the disease’s final stages. Now, in a study published in Nature Neuroscience, a team of molecular biologists and neuropathologists from the UCSF Weill Institute for...
by University of Exeter PET scan of a human brain with Alzheimer’s disease. Credit: public domain Typically characterized as poisonous, corrosive and smelling of rotten eggs, hydrogen sulfide’s reputation may soon get a facelift. In experiments in mice, researchers have shown the foul-smelling gas may help protect aging brain cells against Alzheimer’s disease. The discovery of the biochemical...
New research suggests testing people’s memory over four weeks could identify who is at higher risk of developing Alzheimer’s disease before it has developed. Importantly, the trial found testing people’s ability to retain memories for longer time periods could predict this more accurately than classic memory tests, which test memory over half an hour. The...
Memory loss associated with Alzheimer’s disease (AD) may be able to be restored by inhibiting certain enzymes involved in abnormal gene transcription, according to a preclinical study by researchers at the University at Buffalo. The findings could pave the way toward new treatments for Alzheimer’s disease. The paper will be published in Science Advances. Image credit: University...
by Bob Yirka , Medical Xpress Credit: Pixabay/CC0 Public Domain A team of researchers at Laval University has found evidence that it might be possible to the chances of developing Alzheimer’s disease by editing a key gene in nerve cells. In their paper uploaded to the bioRxiv preprint server, the group describes experiments they conducted that involved editing genes...
by Hildegard Kaulen, Universitaet Tübingen Alzheimer’s disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers including Mathias Jucker from the Hertie Institute for Clinical Brain Research (HIH) in Tübingen and the German Center for Neurodegenerative Diseases (DZNE) show in the...
A fringe theory links microbes in the brain with the onset of dementia. Now, researchers are taking it seriously. Alison Abbott Some scientists think that microbes such as the herpes simplex virus 1 (shown here on an epithelial cell) could trigger some cases of Alzheimer’s disease. Two years ago, immunologist and medical-publishing entrepreneur Leslie Norins offered to...
UPPSALA UNIVERSITY IMAGE: IN ALZHEIMER’S DISEASE, A PROTEIN (PEPTIDE) FORMS CLUMPS IN THE BRAIN AND CAUSES SUFFERERS TO LOSE THEIR MEMORY. IN A RECENTLY PUBLISHED ARTICLE, A RESEARCH GROUP AT UPPSALA UNIVERSITY DESCRIBED. In Alzheimer’s disease, a protein (peptide) forms clumps in the brain and causes sufferers to lose their memory. In a recently published...
Nov 2 2020 Hong Kong Baptist University (HKBU) scientists have invented a novel contrast agent for magnetic resonance imaging (MRI), which enables real-time visualization and detection of the size and number of amyloid-beta in the brain, a main hallmark of Alzheimer’s disease (AD). The invention offers hope for early detection and large-scale routine screening of...
