A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer’s...
UNIVERSITY OF EASTERN FINLAND A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer’s disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of immune cells as a target of future development of new therapies for Alzheimer’s...
Anticholinergic medications are used for many conditions but might also accelerate cognitive decline, especially in older persons with biological or genetic risk factors UNIVERSITY OF CALIFORNIA – SAN DIEGO A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad...
by Ruhr-Universitaet-Bochum Animals and humans have the ability to follow their own position in space through self-motion cues, even in the absence of any other sensory information. “If you get up at night and want to find your way to the bathroom in the dark, you need—in addition to knowing the arrangement of your own...
MEMORIAL SLOAN KETTERING CANCER CENTER Alzheimer’s disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease progression is an active area of research important for developing prevention and treatment strategies. Recent...
by Bob Shepard, University of Alabama at Birmingham The neurons in this image are stained blue, indicating the presence of the BIN1 protein. Points of direct interaction between BIN1 and calcium channels are in purple. Credit: University of Alabama at Birmingham Researchers at the University of Alabama at Birmingham are on the track of a...
Reviewed by Emily Henderson, B.Sc.Sep 3 2020 In a first of its kind study, a University of Houston researcher is examining two common drugs used for dementia in patients with Alzheimer’s disease to determine the extent to which they don’t mix well together and cause a cascading event of side effects, prompting the need for...
by University of Kentucky Research looking at a possible new therapeutic approach for Alzheimer’s disease was recently published in the Journal of Neuroinflammation. The paper out of the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) is titled “Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition”. The...
by Stevens Institute of Technology By detecting subtle differences in the way that Alzheimer’s sufferers use language, researchers at Stevens Institute of Technology have developed an A.I. algorithm that promises to accurately diagnose Alzheimer’s without the need for expensive scans or in-person testing. The software not only can diagnose Alzheimer’s, at negligible cost, with more...
by German Center for Neurodegenerative Diseases CPTX (orange) combines functional domains present in natural synaptic organizing proteins in a unique way. The compound was designed to act as a universal bridge builder for excitatory connections between nerve cells. Credit: DZNE / Alexander Dityatev Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan...
