by University of California, San Francisco Women with Alzheimer’s live longer than men with the disease, and scientists at UC San Francisco now have evidence from research in both humans and mice that this is because they have genetic protection from the ravages of the disease. By virtue of having a second X chromosome, women...
by University of Bristol UK academics and clinicians have collaborated to develop a diagnostic definition of the widely recognised but poorly understood condition, Functional Cognitive Disorder (FCD). Credit: University of Bristol Experts estimate up to one third of people attending specialist memory clinics could have a condition that is commonly mistaken for early dementia. In...
by American Chemical Society larger the dose of opioid, the larger the antibody response. “This was surprising,” Kyzer says. “We saw antibody responses in people who were taking large doses for as little as 6 months.” The scientists are now working on isolating the key opioid antigenic intermediates in the body that prompt the generation...
by St. Jude Children’s Research Hospital Scientists at St. Jude Children’s Research Hospital are advancing understanding of a potential Alzheimer’s disease treatment. The work focuses on LC3-associated endocytosis (LANDO) and its role in neuroinflammation. The results appeared as an advance online publication today in Science Advances. The researchers previously discovered the LANDO pathway in microglial...
Conducting genetic screening in hundreds of autopsied brain samples, investigators identified shared molecular mechanisms in Alzheimer’s disease and LATE, a common brain disorder BRIGHAM AND WOMEN’S HOSPITAL Alzheimer’s disease is one of the most common causes of dementia, and while most people might know someone who is affected by it, the genetic factors behind the...
by Natalie C. Tronson, The Conversation Of all frightening ways that the SARS-COV-2 virus affects the body, one of the more insidious is the effect of COVID-19 on the brain. It is now clear that many patients suffering from COVID-19 exhibit neurological symptoms, from loss of smell, to delirium, to an increased risk of stroke....
FUDAN UNIVERSITY SCIENTISTS FROM FUDAN UNIVERSITY DEVELOPED NOVEL STRATEGIES ACHIEVING ALLOGENEIC MICROGLIA REPLACEMENT IN THE CENTRAL NERVOUS SYSTEM. view more CREDIT: IMAGE CREDIT: XU ET AL, 2020, CELL REPORTS Researchers at Fudan University in Shanghai, China have developed three different techniques that successfully replace almost all malfunctioning microglia – each technique with its own advantage...
Depleting key protein could protect against conditions marked by chronic inflammation UT SOUTHWESTERN MEDICAL CENTER ANTI-REELIN IS A THERAPEUTIC APPROACH THAT SELECTIVELY TARGETS THE VASCULAR BARRIER, BLOCKING INFILTRATION OF INFLAMMATORY CELLS, DEMYELINATION AND, CONSEQUENTLY, PARALYSIS. view more CREDIT: UT SOUTHWESTERN MEDICAL CENTER DALLAS – Aug. 12, 2020 – In an animal model of multiple sclerosis...
Interview conducted by Emily Henderson, B.Sc. News-Medical spoke to Dr. Randall Bateman and Dr. Nicolas Barthélemy from Washington University about their research on Alzheimer’s disease, and their new technique that can detect Alzheimer’s from a blood test. Why did you choose to research Alzheimer’s and its detection? Alzheimer’s disease offers incredible potential for impact. As...
by Salk Institute A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer’s disease. The new research, published online in July 2020 in the journal Redox Biology, also revealed that the drug, CMS121, works by changing how brain...
