Tag: <span>Alzheimer’s disease</span>

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It’s not just Alzheimer’s disease: Research highlights form of dementia
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It’s not just Alzheimer’s disease: Research highlights form of dementia

by University of Kentucky The long-running study on aging and brain health at the University of Kentucky’s Sanders-Brown Center on Aging Alzheimer’s Disease Center has once again resulted in important new findings—highlighting a complex and under-recognized form of dementia. The work was recently published in the Journal of the American Medical Association (JAMA): Neurology. “One...

Repeated head impacts associated with later-life depression symptoms, worse cognitive function
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Repeated head impacts associated with later-life depression symptoms, worse cognitive function

by Boston University School of Medicine Scientists have long believed that a single traumatic brain injury (TBI) earlier in life may contribute to problems with memory, thinking and depression later in life. In most previous studies, however, research failed to examine the possible role of having a history of exposure to repetitive head impacts, including...

How ApoE4 endangers the brain
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How ApoE4 endangers the brain

by Max Delbrück Center for Molecular Medicine Apolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients, including with polyunsaturated fatty acids—which are building blocks of the membranes surrounding the neurons. In addition, certain unsaturated fatty acids are converted into so-called endocannabinoids. These are endogenous...

Different ‘subtypes’ of Alzheimer’s may be linked to different modifications of the tau protein
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Different ‘subtypes’ of Alzheimer’s may be linked to different modifications of the tau protein

by Massachusetts General Hospital A new study reveals a possible biological reason that Alzheimer’s Disease (AD) progresses at different rates in different patients. The study, which was led by Massachusetts General Hospital researchers, focused on tau, a protein found in the neurofibrillary tangles in the brain that are a well-known sign of AD. Tau can...

New indication of a link between Alzheimer’s and diabetes
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New indication of a link between Alzheimer’s and diabetes

by Forschungszentrum Juelich Pathological protein clumps are characteristic of a series of diseases, such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. Scientists at Forschungszentrum Jülich, Heinrich Heine University Düsseldorf, and Maastricht University have now used cryo-electron microscopy to obtain a sharp image for the first time of how individual molecules are arranged in...

Memory impairment in mice reduced by soy derivate that can enter the brain intact
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Memory impairment in mice reduced by soy derivate that can enter the brain intact

Ingestion of the protein fragment improved working and long-term memory in mice treated to simulate Alzheimer’s disease KYUSHU UNIVERSITY In a study that could help one day give a literal meaning to food for thought, researchers from Kyushu University in Japan have reported that a protein fragment that makes its way into the brain after...

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Lancet Neurology publishes results of AFFiRiS’ Phase 1 trial with PD01A in Parkinson’s

Vienna, Austria, June 18, 2020 – AFFiRiS AG, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies (SAITs), today announced that detailed results of the phase 1 clinical program with its lead candidate PD01 in early Parkinson’s disease (PD) patients were published in the peer-reviewed journal The Lancet Neurology. The results of the long-term...

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Researchers uncover new insights into Alzheimer’s disease

by Amy Robinson, Florida State University PET scan of a human brain with Alzheimer’s disease. Credit: public domain A new study by Florida State University researchers may help answer some of the most perplexing questions surrounding Alzheimer’s disease, an incurable and progressive illness affecting millions of families around the globe. FSU Assistant Professor of Psychology...