Novel class of drugs more precisely blocks production of toxic forms of beta-amyloid Scientists at the Massachusetts General Hospital (MGH), in collaboration with colleagues at the University California, San Diego (UCSD), have characterized a new class of drugs as potential therapeutics for Alzheimer’s disease and discovered a piece in the puzzle of how they would...
Tag: <span>Alzheimer’s disease</span>
Post
New ‘plaque destroying’ light therapy could prevent Alzheimer’s disease by blitzing dangerous proteins
Researchers from Rice University in Houston, Texas, developed a probe to target proteins in the brain that cause Alzheimer’s disease More than five million people in the US suffer from the degenerative disease Previous studies have used medication to attempt to target these proteins Experts say this probe could improve medication for the disease Rogue...
Post
‘Ideal biomarker’ detects Alzheimer’s disease before the onset of symptoms
Croatia, New Mexico (October, 2017): Absence of a prefrontal activation during sensory gating of simple tones detects the Alzheimer’s disease (AD) before the occurrence of the first symptoms. Sanja Josef Golubic Ph.D., physicists at the Department of Physics, Faculty of Science, University of Zagreb, reveals the high potential, absolutely non-invasive biomarker of AD pathology in...
Post
Experimental brain technology can rewind Alzheimer’s disease
Alzheimer’s disease is considered a global challenge of the century. Alzheimer’s disease is a thief. It comes and takes away the most precious memories with which people identify themselves. It is a very clever thief. People whom it affects don’t even remember what they have lost—they just feel lost; lost in space and time. Alzheimer’s can...
Post
Do Microbes Trigger Alzheimer’s Disease?
In late 2011, Drexel University dermatology professor Herbert Allen was astounded to read a new research paper documenting the presence of long, corkscrew-shape bacteria called spirochetes in postmortem brains of patients with Alzheimer’s disease.1 Combing data from published reports, the International Alzheimer Research Center’s Judith Miklossy and colleagues had found evidence of spirochetes in 451 of 495 Alzheimer’s brains....
Post
Stabilizing TREM2, a potential strategy to combat Alzheimer’s disease
Uncovering the molecular mechanism behind a rare genetic risk factor of Alzheimer’s disease points to a new therapeutic target A gene called triggering receptor expressed on myeloid cells 2, or TREM2, has been associated with numerous neurodegenerative diseases, such as Alzheimer’s disease, Frontotemporal lobar degeneration, Parkinson’s disease, and Nasu-Hakola disease. Recently, a rare mutation in...
Post
Physicist reports binary marker of preclinical and clinical Alzheimer’s disease
A new technique shows high potential for providing a discrete, non-invasive biomarker of Alzheimer’s disease (AD) at the individual level during both preclinical and clinical stages. The proposed biomarker has a large effect size (0.9) and high accuracy, sensitivity and specificity (100 percent) in identifying symptomatic AD patients within a research sample, according to Sanja...
Post
Undergraduates develop tools to diagnose Alzheimer’s disease before patients show symptoms
A team of seven University of Maryland A. James Clark School of Engineering undergraduates earned the top prize in this year’s National Institutes of Health (NIH) Design by Biomedical Undergraduate Teams (DEBUT) challenge for their efforts to develop low-cost tools to diagnose Alzheimer’s disease before patients show symptoms. “This represents a monumental achievement, not simply...
Post
Could Olfactory Loss Point to Alzheimer’s Disease?
Odor identification tests may help scientists track the evolution of the disease in persons at risk By the time you start losing your memory, it`s almost too late. That`s because the damage to your brain associated with Alzheimer’s disease (AD) may already have been going on for as long as twenty years. Which is why...
Post
Memories could be RE-AWOKEN in Alzheimer’s sufferers: Scientists reactivate brains of dementia-plagued mice with lasers – paving the way to a human cure
Lost memories in Alzheimer’s patients could be brought back with lasers Research team at Columbia University claims memories are not lost but difficult to access Looked at two groups of mice, one with dementia-like disease, one without Studied their brain when they were given memory tests and found the memories are recalled incorrectly Also found...