Tag: <span>Alzheimer’s pathology</span>

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40 Hz Vibrations Reduce Alzheimer’s Pathology, Symptoms in Mouse Models

Tactile stimulation improved motor performance in Alzheimer’s mice models, reduced phosphorylated tau, preserved neurons and synapses, and reduced DNA damage, a new study shows. Evidence that noninvasive sensory stimulation of 40 Hz gamma frequency brain rhythms can reduce Alzheimer’s disease pathology and symptoms, already shown with light and sound by multiple research groups in mice and humans, now...

People who live to be 90+ with superior thinking skills found to be resilient to Alzheimer’s pathology in their brains
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People who live to be 90+ with superior thinking skills found to be resilient to Alzheimer’s pathology in their brains

by University of California, Irvine The 90+ Study, one of the largest studies of its kind in the world, used cognitive assessment test scores from some of the more than 2,000 participants enrolled. The project has produced several significant findings regarding cognitive function, health and lifestyle habits in the oldest-old population information obtained during life. Credit:...

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Alzheimer’s pathology, not cognitive decline, drives neuropsychiatric symptoms

ELSEVIER Philadelphia, March 16, 2022 – Alzheimer’s disease (AD) eventually leads to severe cognitive decline, but most affected individuals also develop distressing neuropsychiatric symptoms. These earlier effects may be more subtle and are not well understood; it remains unclear whether they arise directly from AD pathology or secondarily as psychological reactions due to the cognitive deficits. Now, a...

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Leaking calcium in neurons an early sign of Alzheimer’s pathology

Alzheimer’s disease is known for its slow attack on neurons crucial to memory and cognition.  But why are these particular neurons in aging brains so susceptible to the disease’s ravages, while others remain resilient? In a new study published in the journal Alzheimer’s & Dementia, The Journal of the Alzheimer’s Association, researchers at the Yale...

Increasing glutathione levels lowers Alzheimer’s pathology and improves cognitive decline
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Increasing glutathione levels lowers Alzheimer’s pathology and improves cognitive decline

by CHeBA  Credit: Unsplash/CC0 Public Domain Australian researchers have shown that a dietary supplement that increases the levels of a powerful antioxidant in the brain may represent a novel strategy for the treatment and/or prevention of cognitive impairment and debilitating neurodegenerative diseases such as Alzheimer’s disease. Findings of the study were recently published in Neurochemistry International....