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New approach provides potential vaccine and treatment for Alzheimer’s
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New approach provides potential vaccine and treatment for Alzheimer’s

by University of Leicester Credit: CC0 Public Domain A promising new approach to potentially treat Alzheimer’s disease—and also vaccinate against it—has been developed by a team of UK and German scientists. Both the antibody-based treatment and the protein-based vaccine developed by the team reduced Alzheimer’s symptoms in mouse models of the disease. The research is...

Alzheimer’s drug cited as Medicare premium jumps by $21.60
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Alzheimer’s drug cited as Medicare premium jumps by $21.60

by Ricardo Alonso-Zaldivar  The Biogen Inc., headquarters is shown March 11, 2020, in Cambridge, Mass. Medicare’s “Part B” outpatient premium will jump by $21.60 next year, one of the largest increases ever. Medicare officials told reporters on Friday, Nov. 12, 2021, that about half the increase is attributable to contingency planning if the program has...

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Listening to favourite music improves brain function in Alzheimer’s patients: U of T research

Repeated listening to personally meaningful music induces beneficial brain plasticity in patients with mild cognitive impairment or early Alzheimer’s disease, a new study by researchers at the University of Toronto and Unity Health Toronto suggests. Changes in the brain’s neural pathways correlated with increased memory performance on neuropsychological tests, supporting the clinical potential of personalized,...

International Alzheimer’s clinical trial to test two drugs in combination
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International Alzheimer’s clinical trial to test two drugs in combination

Researchers leading a worldwide clinical trial aimed at finding treatments for Alzheimer’s disease are modifying an arm of the trial to evaluate a combination of drugs targeting two brain proteins: amyloid and tau. The trial – known as the Tau Next Generation Trial (Tau NexGen) – originally was announced with a focus on drugs that...

Has a treatment for Alzheimer’s been sitting on pharmacy shelves for decades? Scientists have two possible candidates
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Has a treatment for Alzheimer’s been sitting on pharmacy shelves for decades? Scientists have two possible candidates

by Delthia Ricks, Medical Xpress PET scan of a human brain with Alzheimer’s disease. Credit: public domain Two drugs approved decades ago not only counteract brain damage caused by Alzheimer’s disease in animal models, the same therapeutic combination may also improve cognition. Sounds like a slam dunk in terms of a cure—but not yet. Researchers...

Research sheds light on how Alzheimer’s progresses in the brain
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Research sheds light on how Alzheimer’s progresses in the brain

by Georg Meisl,  The Conversation Credit: Yurchanka Siarhei/Shutterstock Alzheimer’s disease and other types of dementia affect more than 55 million people worldwide. But the development of effective treatments and cures is progressing slowly. To some extent, this is because we still don’t understand enough about what causes the disease and drives its progression. Myself and my...

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‘Fascinating’ Link Between Alzheimer’s and COVID-19

Megan Brooks Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Risk for Alzheimer’s disease (AD) and susceptibility to severe COVID-19 share a common genetic mechanism involved in the immune response to viruses, investigators report. The findings could lead to new treatment targets to slow progression and severity of both diseases. Investigators found...

Discovery of new role for brain’s immune cells could have Alzheimer’s implications
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Discovery of new role for brain’s immune cells could have Alzheimer’s implications

by Josh Barney,  University of Virginia “Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top expert on microglia. Credit: Dan Addison, University Communications, University of Virginia University of Virginia School of Medicine researchers have revealed a vital but previously unknown role for...

Cancer chemotherapy drug reverses Alzheimer’s symptoms in mice
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Cancer chemotherapy drug reverses Alzheimer’s symptoms in mice

by  University of British Columbia Credit: Pixabay/CC0 Public Domain A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer’s disease, new UBC research has found. The drug, Axitinib, inhibits the growth of new blood vessels in the brain—a feature shared by both cancer tumors and Alzheimer’s disease, but...

New treatments for Alzheimer’s and stroke revealed in several new studies
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New treatments for Alzheimer’s and stroke revealed in several new studies

by  American Physiological Society Credit: Pixabay/CC0 Public Domain The results of three new studies indicate there could be new treatments for Alzheimer’s and stroke. One study reveals a possible link between gum disease and Alzheimer’s. Two other studies explore how the substance sovateltide shows promise for treating neurodegenerative disorders. The research data will be presented virtually...