By Kenneth S. Kosik | Scientific American Research into the brain’s protein-disposal systems, electrical activity and three other areas looks promising Attempts to treat Alzheimer’s have floundered because scientists have spent too little time thinking deeply about the underlying biology of this ailment. Recent advances in understanding the brain’s protein-disposal systems, the role of inflammation,...
New research has revealed greater detail about the brain’s structure, suggesting avenues for future research into Alzheimer’s disease and related illnesses. The brain structure that contains glial cells can provide important insights into Alzheimer’s disease, researchers believe. A new study has revealed more detail about key brain cells. The team of investigators has found that...
By Rich Haridy The link between diseases such as Alzheimer’s and sleep loss has been frequently cited by researchers, and a new study led by scientists from the University of Pennsylvania has discovered a signaling pathway that both regulates sleep and controls the protein aggregations commonly associated with neurodegeneration. It’s hoped the discovery will lead...
by Caleb Stratton, Medical University of South Carolina Individuals with Down syndrome are at a much greater risk of developing Alzheimer’s disease, with inflammation of the brain starting early in life and the risk of Alzheimer’s reaching nearly 80% by the age of 60. The root cause of Alzheimer’s disease is unknown. However, its frequency...
By Dr. Liji Thomas, MD Reviewed by Dr. Jennifer Logan, MD, MPH Why is the difference between AD and other dementias important?People have been talking about dementia and Alzheimer’s disease (AD) for over 100 years now. Yet, in most cases, the difference between them is not clear. Is there a real difference? The answer is...
by Renã A.s. Robinson, The Conversation Blacks are at higher risk for several health conditions in the U.S. This is true for heart disease, hypertension, type 2 diabetes and stroke, which are often chronic diseases. And it is also for Alzheimer’s disease, in which blacks have two times higher incidence rates than whites. So, why...
Neurons die earlier than experts previously thought in Alzheimer’s disease, and stopping the process could prevent the disease from ever developing, finds a new study from Tokyo Medical and Dental University in Japan. Research brings a new understanding of how Alzheimer’s disease develops. Alzheimer’s disease is the leading cause of dementia, and as many as...
Discovered in mice and confirmed in human samples, scientific team become the first to observe how a characteristic of the Presenilin1 gene means it could be used as a biomarker for Alzheimer’s TAYLOR & FRANCIS GROUP Scientists have detected that a previously overlooked gene behavior could potentially lead to a new way to diagnose Alzheimer’s...
by University of Technology, Sydney If we can overcome the loss of a process in the brain called “RNA editing,” we may be able to slow the progress of Alzheimer’s disease and other synaptic disorders, a new study has shown. RNA editing is a genetic mechanism that modifies proteins essential in the connection between nerve cells...
Scientists at Dongguk University successfully treated Alzheimer’s disease in mice using the gene-editing tool CRISPR-Cas9. They used the tool to edit out the Alzheimer’s causing gene in the mice, thereby improving their memory and other cognitive functions. While this is only a first step and much research remains to be done, these promising results put...
