A compound called cambinol shows great promise as a future Alzheimer’s drug. The molecule has halted the spread of the toxic brain protein tau in cell cultures and mice. A brain protein called tau is known to play a key role in the development of Alzheimer’s disease. Our brain cells have a “transport system” made of...
Tag: <span>Alzheimers</span>
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New leads on treating dementia and Alzheimer’s
A new study by scientists in Australia and the US provides an explanation for why clinical trials of drugs targeting proteins in the brain that were thought to cause dementia and Alzheimer’s have failed. The study has opened the way for potential new treatments with existing drugs. Published online in the journal Human Molecular Genetics, the researchers...
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Music activates regions of the brain spared by Alzheimer’s disease
Ever get chills listening to a particularly moving piece of music? You can thank the salience network of the brain for that emotional joint. Surprisingly, this region also remains an island of remembrance that is spared from the ravages of Alzheimer’s disease. Diagram of brain networks involved in processing attention. Researchers at the University of Utah...
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How the brain’s ‘immune memory’ may lead to Alzheimer’s
A new study shows that microglia, which are the immune cells of the central nervous system, can “remember” inflammation. This “memory” influences how the cells react to new stimuli and deal with a toxic plaque in the brain, a marker of Alzheimer’s disease. The brain’s immune cells remember previous inflammation. Microglia, sometimes referred to as...
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Alzheimer’s: Scientists find the cause of evening agitation
A new study has uncovered a biological clock circuit that may explain why people with Alzheimer’s disease or other forms of dementia can become more agitated or aggressive in the early evening. People with Alzheimer’s can feel more agitated during the evening. The researchers hope that their findings will lead to new treatments that help...
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Alzheimer’s Disease Gene Successfully Removed From Human Brain: Is This The Cure We’ve Been Waiting For?
Scientists were able to successfully remove a gene that caused Alzheimer’s disease from the human brain, possibly paving the way for a new kind of treatment against the dreaded illness. Scientists were able to successfully remove apoE4, a gene that caused Alzheimer’s disease, from the human brain. The research might be science’s best shot at...
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New blood test useful to detect people at risk of developing Alzheimer’s disease
Heidelberg, 6 April 2018 – There is, as yet, no cure for Alzheimer’s disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention. Alzheimer’s disease is thought to begin long before patients show...
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Alzheimer’s: This protein may halt brain injury
Antibodies that can remove toxic protein plaques in the brains of mice may lead to treatments that halt the brain damage caused by Alzheimer’s disease. What role do antibodies (depicted here) have in treating Alzheimer’s? This was the conclusion that researchers came to after investigating antibodies that target the apolipoprotein E (APOE) protein in a...
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Ibuprofen could stop Alzheimer’s, say researchers
You may have taken ibuprofen today, be it to ease a headache or alleviate back pain. But there might be more to this common medication than pain relief; a new paper suggests that a daily dose of ibuprofen could prevent Alzheimer’s disease. Researchers say that ibuprofen could ward off Alzheimer’s if taken every day. Led...
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Anti-Alzheimer’s antibodies clean out brain plaques in mice
Researchers from the Washington University School of Medicine have tested a new weapon in the fight against Alzheimer’s. In mice tests, the team has demonstrated an antibody that can clear away the disease’s characteristic build-up of proteins in the brain, which may lead to an early-stage treatment to prevent symptoms from occurring. Fragments of a...