06 Sep 2024 Could one tiny little amino acid derivative make Alzheimer’s disease a whole lot worse? In the August 25 Science, researchers led by Katrin Andreasson, Stanford University School of Medicine, report that, in response to oligomers of Aβ or tau, astrocytes produce copious amounts of the tryptophan metabolite kynurenine, which scuppers glycolysis and...
Phase 3 trial of supplement proposed, new diagnostic tool to be validated.Peer-Reviewed Publication UNIVERSITY OF ALBERTA University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID. In research published today in Cell Reports Medicine, the team says it has...
by Universitat Pompeu Fabra – Barcelona Graphical abstract. Credit: Cell Metabolism (2022). DOI: 10.1016/j.cmet.2022.04.001 Researchers from the Girona Biomedical Research Institute (IDIBGI) and Pompeu Fabra University (UPF) in Barcelona, Spain, have identified the role of proline, an amino acid, in humans, mice and flies suffering depression. The results, published in the scientific journal Cell Metabolism, also associate the...
For adults undergoing fracture fixation, conditionally essential amino acid (CEAA) supplementation is associated with a reduction in postoperative complications, according to a study published online March 14 in the Journal of Bone & Joint Surgery. Nathan R. Hendrickson, M.D., from the University of Iowa in Iowa City, and colleagues conducted a prospective, randomized controlled trial (RCT)...
By IAN RANDALL FOR MAILONLINE A diet low in serine, an amino acid in meat, fish and eggs — taken in tandem with drugs to stop its production — may provide a new approach to cancer treatment. As they grow more aggressively, cancer cells are more dependant on serine — a protein building block — than...
The shells of crustaceans and wood waste such as branches pruned from trees usually end up in landfills. These waste materials get a new lease of life to become nutritional supplements and medicine, with the help of this new process. Associate professor Yan Ning and assistant professor Zhou Kang from NUS Chemical and Biomolecular Engineering led the...
A team of researchers from the University of Toronto’s Faculty of Applied Science & Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury. The new version of the enzyme is more stable and could lead to treatments for reversing...
Sleep myoclonus is involuntary, nonrhythmic muscle twitching that occurs either as a person falls asleep or during sleep. Sleep myoclonus is not a disease but a symptom of several different conditions. Sleep myoclonus can also happen without a known cause. In this article, we discuss what sleep myoclonus is, its causes, and how doctors treat...
Ingestion of the protein fragment improved working and long-term memory in mice treated to simulate Alzheimer’s disease KYUSHU UNIVERSITY In a study that could help one day give a literal meaning to food for thought, researchers from Kyushu University in Japan have reported that a protein fragment that makes its way into the brain after...
by Monash University Led by Dr. Adam Rose , the recent finding, published in Nature Communications, shows that by reducing the amount of two amino acids—threonine and tryptophan—in young healthy mice, they were able to burn more calories than they consumed, without calorie reduction, keeping them lean and healthy and without the side-effect of lower...
